DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4461 and cryaa

DIOPT Version :9

Sequence 1:	NP_648304.1	Gene:	CG4461 / 39074	FlyBaseID:	FBgn0035982	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_694482.1	Gene:	cryaa / 100000769	ZFINID:	ZDB-GENE-020508-1	Length:	173	Species:	Danio rerio

Alignment Length:	148	Identity:	42/148 - (28%)
Similarity:	68/148 - (45%)	Gaps:	33/148 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 YDFQLYPYLWDDSRLWWPSPHTSRSDLLRPLDELVSRRVRNQLIQSTPYEWAHPMRWDNYYSG-E 89
            :|:.|:|:.            ||          .||...|:.|.::.         .|:..|| .
Zfish    30 FDYDLFPFT------------TS----------TVSPYYRHSLFRNI---------LDSSNSGVS 63

  Fly    90 RVHVDEKGFRIDIDVRQFHPHDIVVKTNDDYVIVQGNHNRRDEGSNGLVERHFVRKYLLPRGYNA 154
            .|..|.:.|.:.:||:.|.|.::.||..||||.:||.|..|.: .:|.:.|.|.|:|.||...:.
Zfish    64 EVRSDREKFTVYLDVKHFSPDELSVKVTDDYVEIQGKHGERQD-DHGYISREFHRRYRLPSNVDQ 127

  Fly   155 NEVISDISSDGILTIKAP 172
            :.:...:|:||:||:..|
Zfish   128 SAITCTLSADGLLTLCGP 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4461	NP_648304.1	metazoan_ACD	94..169	CDD:107247	27/74 (36%)
cryaa	NP_694482.1	Crystallin	1..48	CDD:278926	7/39 (18%)
		alpha-crystallin-Hsps_p23-like	61..146	CDD:294116	31/86 (36%)
		IbpA	<64..146	CDD:223149	30/83 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	1	1.000	-	-		FOG0000383
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45640
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X393
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920