DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp67Bc and Hsp27

DIOPT Version :9

Sequence 1:	NP_523994.1	Gene:	Hsp67Bc / 39071	FlyBaseID:	FBgn0001229	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001287001.1	Gene:	Hsp27 / 39078	FlyBaseID:	FBgn0001226	Length:	213	Species:	Drosophila melanogaster

Alignment Length:	193	Identity:	80/193 - (41%)
Similarity:	107/193 - (55%)	Gaps:	43/193 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 YGHDMF-PNRMYRRLHSRQHHDLDLHTLGLIARM-----GAHAHHLVANKR-----NGELAALSR 71
            :.||:| |.|:           |..:||||..|.     .:|.||...::|     |..|.|:.:
  Fly    34 HAHDLFHPRRL-----------LLPNTLGLGRRRYSPYERSHGHHNQMSRRASGGPNALLPAVGK 87

  Fly    72 GGASNKQGNFEVHLDVGLFQPGELTVKLVNECIVVEGKHEEREDDHGHVSRHFVRRYPLPKEFDS 136
            .|       |:|.:||..|:|.|||||:|:..:|||||||||||.||.:.|||||:|.|||.||.
  Fly    88 DG-------FQVCMDVSQFKPNELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLPKGFDP 145

  Fly   137 DAIVSTLSEDGVLNITVPPLVSKEELK-ERIIPIKHVGPSDL-------------FQNGNGHK 185
            :.:|||:|.||||.:..||..|||:.| |||:.|:..||:.|             .:||:|.|
  Fly   146 NEVVSTVSSDGVLTLKAPPPPSKEQAKSERIVQIQQTGPAHLSVKAPAPEAGDGKAENGSGEK 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp67Bc	NP_523994.1	metazoan_ACD	75..154	CDD:107247	44/78 (56%)
Hsp67Bc	NP_523994.1	IbpA	<79..170	CDD:223149	53/91 (58%)
Hsp27	NP_001287001.1	metazoan_ACD	86..163	CDD:107247	45/83 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452097
Domainoid	1	1.000	51	1.000	Domainoid score	I4315
eggNOG	1	0.900	-	-		E1_KOG3591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	56	1.000	Inparanoid score	I2586
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	1	1.000	-	-		FOG0000383
OrthoInspector	1	1.000	-	-		otm14686
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45640
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X393
	10	9.900