DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hsp67Bc and Hspb2

DIOPT Version :10

Sequence 1:NP_523994.1 Gene:Hsp67Bc / 39071 FlyBaseID:FBgn0001229 Length:199 Species:Drosophila melanogaster
Sequence 2:NP_569115.1 Gene:Hspb2 / 161476 RGDID:70914 Length:182 Species:Rattus norvegicus


Alignment Length:87 Identity:37/87 - (42%)
Similarity:50/87 - (57%) Gaps:3/87 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    71 RGGASN---KQGNFEVHLDVGLFQPGELTVKLVNECIVVEGKHEEREDDHGHVSRHFVRRYPLPK 132
            |.|||.   .:|.|:..|||..|.|.|:||:.|:..:.|..:|.:|.|.||.|||.|.|.|.||.
  Rat    61 RAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPA 125

  Fly   133 EFDSDAIVSTLSEDGVLNITVP 154
            :.|...:.:.||.||:||:..|
  Rat   126 DVDPWRVRAALSHDGILNLEAP 147

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hsp67BcNP_523994.1 metazoan_ACD 75..154 CDD:107247 33/81 (41%)
Hspb2NP_569115.1 Crystallin <21..55 CDD:425732
alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins. 67..148 CDD:469641 33/81 (41%)
Blue background indicates that the domain is not in the aligned region.

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