Protein Alignment CG4452 and FAM76A

DIOPT Version :10

• Sequence 1: NP_648303.1
• Gene: CG4452 / 39069
• FlyBaseID: FBgn0035981
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_001137384.1
• Gene: FAM76A / 199870
• HGNCID: 28530
• Length: 341
• Species: Homo sapiens
• Alignment Length: 352
• Identity: 136/352 - (38%)
• Similarity: 195/352 - (55%)
• Gaps: 56/352 - (15%)

  Fly     6 LFACSKCFSRHLYEELSSGQQLCKGCRGSTSVGKCTYCRSEFQ---------------------- 48
            |:||:||..|..:|.||.||||||.||.:..|.||||||:|:|
Human     4 LYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQERLECNGTISAHCNLHLPGSS 68

  Fly    49 --PATKSQSA----------CKKCEHYLGKYGKPSACECCKIVAAFGGSKCMRCASYEAKYGPPV 101
              ||:.|:.|          ||||...:..||.|..|:.|.|:|||.|:||.||.:.|.|||||.
Human    69 DSPASSSRVAGITGIKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPY 133

  Fly   102 QCDECKLRSAFDRRDENKKVNGKLLCWLCACAYKRALLKAQQEGRIPMSKKRPHEKTSS--SHRD 164
            .|::||.:.||||:|:.|||:||||||||..:|||.|.|.:::        |.|..:||  .|::
Human   134 SCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQ--------RKHLSSSSRAGHQE 190

  Fly   165 SAAAKKPSRNELGKSGSGANNSGVN-AVSGAGLDLPDKISRGNG--GNGTIAAPAAITVDTNSSD 226
                 |...:.|  ||.|..||... :.|....::|.|.|:...  .||...:| .:.:|:..:|
Human   191 -----KEQYSRL--SGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSP-DLALDSPGTD 247

  Fly   227 HVVAITYLKERIASLEKRLNQKDKELLEKDKQLTELKGKNFEKENDMRNRLKEVERLHDMKVDNL 291
            |.|.|..|||.:|:|:|.|:|||:.:|||:|::||||.....:|:.||.::.::|:.|....:.|
Human   248 HFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 312

  Fly   292 NRKIASVLKELAVLKKS-SNKKTAAIS 317
            ..|...:||:.|.|.|| .::|:.||:
Human   313 QAKNRELLKQAAALSKSKKSEKSGAIT 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4452	NP_648303.1	FAM76	6..310	CDD:464993	133/343 (39%)
FAM76A	NP_001137384.1	FAM76	4..326	CDD:464993	130/337 (39%)