Protein Alignment CG4452 and FAM76B

DIOPT Version :10

• Sequence 1: NP_648303.1
• Gene: CG4452 / 39069
• FlyBaseID: FBgn0035981
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_653265.3
• Gene: FAM76B / 143684
• HGNCID: 28492
• Length: 339
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 131/343 - (38%)
• Similarity: 191/343 - (55%)
• Gaps: 54/343 - (15%)

  Fly     1 MSGKVLFACSKCFSRHLYEELSSGQQLCKGCRGSTSVGKCTYCRSEFQPATKSQSACKKCEHYLG 65
            |:...|:||:||..|:.:||||.||||||.||.:..:.||||||||||..:|:.:.||||...:.
Human     1 MAASALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVK 65

  Fly    66 KYGKPSACECCKIVAAFGGSKCMRCASYEAKYGPPVQCDECKLRSAFDRRDE-NKKVNGKLLCWL 129
            ::|.|..|:.|.|:|||.|:||.||.:.|.|||||..|::||.:.||||::| .:||:|||||||
Human    66 QFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWL 130

  Fly   130 CACAYKRALLKAQQEGRIPMSKKRPHEKTSSS--------------------HRDSAAAKKPS-- 172
            |..:|||.|.|.:::.:   |....|..:|||                    ||.|::..|.|
Human   131 CTLSYKRVLQKTKEQRK---SLGSSHSNSSSSSLTEKDQHHPKHHHHHHHHHHRHSSSHHKISNL 192

  Fly   173 --RNELG------KSGSGANNSGVNAVSGAGLDLPDKISR-----GNGGNGTIAAPAAITVDTNS 224
              ..|.|      ||.:...|           :.|.|..:     .||.:.:|...|    |:..
Human   193 SPEEEQGLWKQSHKSSATIQN-----------ETPKKKPKLESKPSNGDSSSINQSA----DSGG 242

  Fly   225 SDHVVAITYLKERIASLEKRLNQKDKELLEKDKQLTELKGKNFEKENDMRNRLKEVERLHDMKVD 289
            :|:.|.|:.|||.:.||::.|.|:|:.:|||||:|||||.....:|:::|.::..:|:.|...|:
Human   243 TDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVE 307

  Fly   290 NLNRKIASVLKELAVLKK 307
            .|..|...:||::|.|.|
Human   308 QLQAKNRELLKQVAALSK 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4452	NP_648303.1	FAM76	6..310	CDD:464993	130/338 (38%)
FAM76B	NP_653265.3	FAM76	6..328	CDD:464993	130/338 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..243		22/116 (19%)