Protein Alignment Klp67A and HIK

DIOPT Version :10

• Sequence 1: NP_523992.2
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_173273.2
• Gene: HIK / 838418
• AraportID: AT1G18370
• Length: 974
• Species: Arabidopsis thaliana
• Alignment Length: 811
• Identity: 210/811 - (25%)
• Similarity: 356/811 - (43%)
• Gaps: 156/811 - (19%)

  Fly     9 IKVAVRVRPYNVRELEQKQRSIIKVMDRSALLFDPDEEDDEFFFQGAKQPYRDITKRMNKKLTME 73
            |.|.||:||.|.|||..|.:...:.::...::..|                 .:.:|::.:.:..
plant    32 IVVTVRLRPMNKRELLAKDQVAWECVNDHTIVSKP-----------------QVQERLHHQSSFT 79

  Fly    74 FDRVFDIDNSNQDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLGSEAHPGLTYLTMQDL 138
            ||:||..::..::::|:....:..:.|.|.|.::|.||.|.:|||:||      .|:|...:.|:
plant    80 FDKVFGPESLTENVYEDGVKNVALSALMGINATIFAYGQTSSGKTYTM------RGVTEKAVNDI 138

  Fly   139 FDKIQAQSDVRKFDVGVSYLEVYNEHVMNLL-TKSG-PLKLRED-NNGVVVSGLCLTPIYSAEEL 200
            ::.| .::..|.|.:.:|.||:|||:|.:|| :.|| .|||.:| ..|.||..|......:...|
plant   139 YNHI-IKTPERDFTIKISGLEIYNENVRDLLNSDSGRALKLLDDPEKGTVVEKLVEETANNDNHL 202

  Fly   201 LRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRITERK-TDTKRT--VKLSMIDLAGSERAAST 262
            ..::.:..:.|....|..|..|||||.|.::.|:.|.|: :|..|:  ..|:.:||||||||:.:
plant   203 RHLISICEAQRQVGETALNDTSSRSHQIIRLTIQSTHRENSDCVRSYMASLNFVDLAGSERASQS 267

  Fly   263 KGIGVRFKEGASINKSLLALGNCINKLADGLK--HIPYRDSNLTRILKDSLGGNCRTLMVANVSM 325
            :..|.|.:||..||.||:.|...|.||:.|.:  |||||||.|||||:.|||||.||.::..:|.
plant   268 QADGTRLREGCHINLSLMTLTTVIRKLSVGKRSGHIPYRDSKLTRILQHSLGGNARTAIICTLSP 332

  Fly   326 SSLTYEDTYNTLKYASRAKKIRTTLKQNVLKSKMPTEFYVKKIDEVVAENERLKERNKALEAKAT 390
            :....|.:.|||.:|:|||::......|:                ||::.:.:|...|.:.....
plant   333 ALAHVEQSRNTLYFANRAKEVTNNAHVNM----------------VVSDKQLVKHLQKEVARLEA 381

  Fly   391 QLERAGNSGFDPLELKTWYSKIDAVYAAARQLQEHVLGMRSKIKNINYRQTLKKELEEFRKLMCV 455
            :....|.|.....::              :|::..:..:|.:      |...:.:|||.|:.:..
plant   382 ERRTPGPSTEKDFKI--------------QQMEMEIGELRRQ------RDDAQIQLEELRQKLQG 426

  Fly   456 DQRVCQED------------FRRFANYMSTLTSQMEKYKEELPSWLSKMEIAYQDL--ESLKREV 506
            ||   |::            .|:..:|...:|...|.      ..|::.|.|.:..  :|:.|:
plant   427 DQ---QQNKGLNPFESPDPPVRKCLSYSVAVTPSSEN------KTLNRNERARKTTMRQSMIRQ- 481

  Fly   507 NKSKAYQILIVYVKYKDLELQLTKQNIFNNHVNAINQELVENLDLMRKSFRTACEVL-NQTYDRL 570
            :.:..:.::....|.:.|:.||             .:|..:.|::::|  ..||..| ||  |..
plant   482 SSTAPFTLMHEIRKLEHLQEQL-------------GEEATKALEVLQK--EVACHRLGNQ--DAA 529

  Fly   571 EDGQKLTPEIEAVFERLLRKMRFADSEANTKMAEMNPLAVPVALRSSAQEEE----EPTCSLTAS 631
            :...||..||        |:||.....|..|  |:..:..|....|:..:||    ....|..|:
plant   530 QTIAKLQAEI--------REMRTVKPSAMLK--EVGDVIAPNKSVSANLKEEITRLHSQGSTIAN 584

  Fly   632 AKKRQRQAAQSDDDLHLSMEDFDSQDTESDSEELHRTFKRPRNL---------NETQVL-GPCSS 686
            .:::.....:|.|.|.:|:....|...|:...:.|....:.:.|         |....| .|||.
plant   585 LEEQLESVQKSIDKLVMSLPSNISAGDETPKTKNHHHQSKKKKLLPLTPSSASNRQNFLKSPCSP 649

  Fly   687 SSSS-------------STSSSSSARKALTATVTKPRTVQQRLVSDLISDQNVRGGNEKIKKALL 738
            .|:|             ..::||:||.|.|...::..|.|:...|..:|.:....|..:.....:
plant   650 LSASRQVLDCDAENKAPQENNSSAARGATTPQGSEKETPQKGEESGDVSSREGTPGYRRSSSVNM 714

  Fly   739 KSNHFTAQGLQRTLAAASLAKENVKYNANYV 769
            |.       :|:....|  |:|||:....||
plant   715 KK-------MQQMFQNA--AEENVRSIRAYV 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp67A	NP_523992.2	KISc_KIP3_like	8..346	CDD:276821	120/344 (35%)
HIK	NP_173273.2	KISc_CENP_E	31..353	CDD:276825	120/344 (35%)
		COG4913	<467..>599	CDD:443941	35/159 (22%)
		DUF3490	791..955	CDD:463424