DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Klp67A and AT3G49650

DIOPT Version :9

Sequence 1:	NP_001286999.1	Gene:	Klp67A / 39068	FlyBaseID:	FBgn0004379	Length:	814	Species:	Drosophila melanogaster
Sequence 2:	NP_190534.1	Gene:	AT3G49650 / 824127	AraportID:	AT3G49650	Length:	813	Species:	Arabidopsis thaliana

Alignment Length:	857	Identity:	247/857 - (28%)
Similarity:	406/857 - (47%)	Gaps:	153/857 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPS------EQHTNIKVAVRVRPYNVRELEQKQRSIIKVMD-RSALLFDPDEEDDEFFFQGAKQP 58
            |||      ::.|.:.|||:.||...:|   :.|.|::|.: :..::.|||...|
plant     1 MPSIRAPAAKKTTTLTVAVKCRPLMEKE---RGRDIVRVNNSKEVVVLDPDLSKD---------- 52

  Fly    59 YRDITKRMNKKLTMEFDRVFDIDNSNQDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLG 123
            |.|..:...|:....||..|..:::|::::...:: ::.:|::|.|.:||.||:||:|||:||:|
plant    53 YLDRIQNRTKEKKYCFDHAFGPESTNKNVYRSMSS-VISSVVHGLNATVFAYGSTGSGKTYTMVG 116

  Fly   124 SEAHPGLTYLTMQDLFDKIQAQSDVRKFDVGVSYLEVYNEHVMNLLTK-SGPLKLRED-NNGVVV 186
            :.:.|||..|::..:||.|::.....:|:|..||||||||.:.:||.| ||.|:|||| ..|:||
plant   117 TRSDPGLMVLSLNTIFDMIKSDKSSDEFEVTCSYLEVYNEVIYDLLEKSSGHLELREDPEQGIVV 181

  Fly   187 SGLCLTPIYSAEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRITERKTDTKRTVKLSMI 251
            :||....::||:.:|.:|.||||.|....|:.|..||||||:.::.::..::..:.....||:::
plant   182 AGLRSIKVHSADRILELLNLGNSRRKTESTEMNGTSSRSHAVLEIAVKRRQKNQNQVMRGKLALV 246

  Fly   252 DLAGSERAASTKGIGVRFKEGASINKSLLALGNCINKLA----DGLKHIPYRDSNLTRILKDSLG 312
            |||||||||.|...|.:.::||:||:|||||.||||.|.    .||.::|||:|.|||||||.|.
plant   247 DLAGSERAAETNNGGQKLRDGANINRSLLALANCINALGKQHKKGLAYVPYRNSKLTRILKDGLS 311

  Fly   313 GNCRTLMVANVSMSSLTYEDTYNTLKYASRAKKIRTTLKQNVLKSKMPTEFYVKKIDEVVAENER 377
            ||.:|:|||.:|.:...|..|.||||||.|||:|:|.:::|:.........|.:.||.:.:|..:
plant   312 GNSQTVMVATISPADSQYHHTVNTLKYADRAKEIKTHIQKNIGTIDTHMSDYQRMIDNLQSEVSQ 376

  Fly   378 LKERNKALEAKATQL-ERAGNSGFDPLE--LKTWYSKIDA--------------VYAAARQLQEH 425
            ||          ||| |:.......|.|  ::...|.:|.              :..|..:|:|.
plant   377 LK----------TQLAEKESQLSIKPFERGVERELSWLDGLSHQISENVQDRINLQKALFELEET 431

  Fly   426 VLGMRSKIKNIN---YRQTLKKELEE---FRKLMCVDQRVCQEDFRRFANYMSTLTSQMEKYKEE 484
            .|..|:::::::   .:|..:|::.|   .|:.:.:|.  .:::.....||...: .:.||::.|
plant   432 NLRNRTELQHLDDAIAKQATEKDVVEALSSRRQVILDN--IRDNDEAGVNYQRDI-EENEKHRCE 493

  Fly   485 LPSWLSKMEIAYQDLESLKREVNKS-----KAYQILIVYVKYKDLELQLTKQNIFN--------- 535
            |...|:         |::....||:     ..|::|.:.......|:.:..|.|:|
plant   494 LQDMLN---------EAINNNGNKTYLHILNQYKLLGMGNTELQFEMAMRDQIIYNQREAQRNLW 549

  Fly   536 NHVNAINQELVENLDLMRKSFRTACEVLNQTYDRLEDGQKLTPEIEAVFERL-LRKMRFADSEAN 599
            |.:..:..|..:..||..|...|           :||...:     |:|..| .||...:...||
plant   550 NLLMGLGVEEKQVFDLAAKQGIT-----------IEDWSSI-----ALFPGLPYRKQTPSFIPAN 598

  Fly   600 -------------TKMAEMNPLAVPVALRSSAQEEEEPTCSLTA----SAKKRQRQAAQSDDDLH 647
                         |..:..:|        ||..::..||.:|..    |:....||...:..:|.
plant   599 IPFVGHSYSKSSCTFQSYQDP--------SSKGQQWAPTPTLCREEHHSSYYFMRQEPPAFVNLR 655

  Fly   648 LSMEDF---DSQDTESDSEELHRTFKRPRNLNET---QVLGPCSSSSS------SSTSSSSSARK 700
            .|.:.:   ....:..|:...||....|:.:|.:   ...||....:.      ::||..||.|.
plant   656 KSHDGWVGGSRPASRIDTGGNHRRVSYPQTVNNSSPRMASGPTFYQTPQREMLLNTTSPYSSPRV 720

  Fly   701 ALTATVTKPRTVQ-----QRLVSDLISDQNVRGGNEKIKKALLKSNHFTAQGLQRTLAAASLAKE 760
            .|....|.| :||     .|.|:       ||.|:.....|....:...|:..||....:.|:..
plant   721 GLINGATTP-SVQPFYGSPRAVT-------VRNGSYNTPLAPAAVSTKGARNQQRVFGTSPLSGT 777

  Fly   761 NVKYNANYVRKS 772
            ....|::|.:.|
plant   778 KGVKNSSYGQNS 789

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klp67A	NP_001286999.1	KISc	8..353	CDD:214526	145/351 (41%)
Klp67A	NP_001286999.1	KISc_KIP3_like	8..346	CDD:276821	143/344 (42%)
AT3G49650	NP_190534.1	KISc_KIP3_like	14..345	CDD:276821	143/344 (42%)
		Kinesin	21..345	CDD:278646	140/337 (42%)
		FAM76	<355..437	CDD:292665	18/91 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D703086at2759
OrthoFinder	1	1.000	-	-		FOG0000448
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100835
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720