Protein Alignment Klp67A and kif22

DIOPT Version :9

• Sequence 1: NP_001286999.1
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_001107063.1
• Gene: kif22 / 561788
• ZFINID: ZDB-GENE-080204-34
• Length: 634
• Species: Danio rerio
• Alignment Length: 605
• Identity: 174/605 - (28%)
• Similarity: 299/605 - (49%)
• Gaps: 89/605 - (14%)

  Fly     3 SEQHTNIKVAVRVRPYNVRELEQKQRSIIKVMDRSALLFDPDEEDDEFFFQGAKQPYRDITKRMN 67
            |::.:.::||||:|||               ||:.      ||:.:....:|......:|....|
Zfish    14 SKRTSRVRVAVRLRPY---------------MDKQ------DEKSEGSCVRGLGPQKLEIINWRN 57

  Fly    68 KKLTMEFDRVFDI----DNSNQDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLGSEAHP 128
            ...|:::.  ||:    :.:.|::|.....|::..:|||.|.|||.||.||||||.|||||:..|
Zfish    58 ATETLQYQ--FDVFHGEETTQQEVFLTSVKPILPHILNGQNASVFAYGPTGAGKTHTMLGSQEQP 120

  Fly   129 GLTYLTMQDLFDKIQAQ---SDVRKFDVGVSYLEVYNEHVMNLLTK-SGPLKLRED-NNGVVVSG 188
            |:....::::|:.:.||   .|..::.:|:||||:|||.|::||:. |..|.:||| :..:::.|
Zfish   121 GVIPRAVKEVFNLVGAQKKEQDGWEYSIGMSYLEIYNEKVLDLLSPGSQDLPIREDKDRNILIPG 185

  Fly   189 LCLTPIYSAEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRITER-KTDTKRTVKLSMID 252
            |..||:.|..:.....:..:.:||...|..|..|||||||..:.:..::| ....::|.||.::|
Zfish   186 LTHTPLSSFADFDTHFIPASLNRTTASTKLNQRSSRSHAILLIKVVKSQRGPPHRQQTGKLYLVD 250

  Fly   253 LAGSERAASTKGIGVRFKEGASINKSLLALGNCINKLADGL-KHIPYRDSNLTRILKDSLGGNCR 316
            |||||....|...|:|.||..:||.||..|...::.|..|. ..:|||||.|||:|:|||||:..
Zfish   251 LAGSEDNRRTGNQGIRLKESGAINLSLFTLSKVVDALNTGAGGRVPYRDSKLTRLLQDSLGGSAH 315

  Fly   317 TLMVANVSMSSLTYEDTYNTLKYASRAKKI--RTTLKQNVLKSKMPTEFYVKKIDEVVAENERLK 379
            ::|:.|::.....|.||::.|.:|:::|:|  |..:::.||   .||          :|..:|.:
Zfish   316 SVMITNIAPEYKYYFDTFSALNFAAKSKQIVNRPFVRETVL---APT----------IAPGKRTR 367

  Fly   380 ERNKA------LEAKATQLERAGNSGFDPLELKTWYSKIDAVYAAARQLQEHVLGMRSKIKNINY 438
            |..:|      ...::.:.::|.:|...||..::  |...:|......|::.::|...: :.:|.
Zfish   368 EEQEAGGSGEPQNKRSKEGKKAEHSPSPPLHPQS--SPDSSVLDRLLALEKMMMGSAER-ERLNL 429

  Fly   439 RQTLKKELEEFRKLMCVDQRVCQEDFRRFANYMSTLTSQMEK----YKEELPSWLSKMEIA---- 495
            .:|:.:..:|.:  |..:::...||.....|.....|.:..|    :|.:||....|...|
Zfish   430 LKTVAQSRKEIQ--MLKEKQKELEDKANMFNKQKETTEKESKDALLFKTDLPPLHRKQSTAAKPR 492

  Fly   496 ----------YQDLESLKREVNKSKAYQILIVYVKYKDLELQLT--KQNIFNN--HVNAINQELV 546
                      ...::.|::.....|..|.|   ||.|.::.::.  |:||..:  .|..:|.|
Zfish   493 KQQAVVTPLQVSQVQPLQQCAVVCKPSQTL---VKKKRVQTEVCDGKENIGVDLPPVEDVNWE-- 552

  Fly   547 ENLD--LMRKSFRTACEVLN 564
            ..||  |:.:|.:...:.||
Zfish   553 SRLDPALLEQSRKKILQTLN 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp67A	NP_001286999.1	KISc	8..353	CDD:214526	124/357 (35%)
		KISc_KIP3_like	8..346	CDD:276821	122/348 (35%)
kif22	NP_001107063.1	KISc	19..351	CDD:214526	124/354 (35%)
		KISc_KID_like	19..343	CDD:276827	121/346 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	357..406		11/60 (18%)
		HHH_3	571..620	CDD:289597	2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000448
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910