Protein Alignment Klp67A and Klp31E

DIOPT Version :9

• Sequence 1: NP_001286999.1
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_001162935.1
• Gene: Klp31E / 34422
• FlyBaseID: FBgn0032243
• Length: 1048
• Species: Drosophila melanogaster
• Alignment Length: 917
• Identity: 248/917 - (27%)
• Similarity: 394/917 - (42%)
• Gaps: 224/917 - (24%)

  Fly     7 TNIKVAVRVRPYNVRELEQKQRSIIKVMDRSALLFDPDEEDDEFFFQGAKQPYRDITKRMNKKLT 71
            ::::||||:||.|.|||....|....|     .|.:|.      .|.|:.:.:
  Fly    12 SSVRVAVRIRPQNSRELIDMCRICTTV-----TLGEPQ------IFLGSDKAF------------ 53

  Fly    72 MEFDRVFDIDNSNQ-DLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLGSEAHP------- 128
             .||.||| .|||| |::.:|...|||:.|:|||.:|..||.||:|||:||.....|.
  Fly    54 -TFDYVFD-TNSNQCDIYSDCVEKLVDSTLHGYNATVLAYGQTGSGKTYTMGTGFDHESESSDSV 116

  Fly   129 --GLTYLTMQDLFDKIQ-----------AQSDVRKFDVGVSYLEVYNEHVMNLL---TKSGPLKL 177
              |:....::.:|..|:           |.....:|.:.|.|:|:|||.:.:||   .|:...|:
  Fly   117 QLGIIPRAVRHIFSGIEQLEGSSTSEHPAAGGSPQFSLAVQYIELYNEDIFDLLDPFNKNSNFKI 181

  Fly   178 REDNNG-VVVSGLCLTPIYSAEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIR------- 234
            .||.:| :.:||..:.|||...:.|:.|..|...||...|..|.:||||||:|.:.:|
  Fly   182 HEDASGQITISGASIKPIYQPHDALKYLQQGALARTTASTKMNDQSSRSHALFTIFVRRQRLLTP 246

  Fly   235 ---ITERKTDTKRTVKLSMIDLAGSERAASTKGIGVRFKEGASINKSLLALGNCINKLADGLK-- 294
               :.:...:| .|.|...:|||||||...|:..|.|.:||.|||..||||||||:.|.|..|
  Fly   247 SDNVPDNDLET-LTSKFHFVDLAGSERLKRTQATGERAREGISINCGLLALGNCISALGDKSKRA 310

  Fly   295 -HIPYRDSNLTRILKDSLGGNCRTLMVANVSMSSLTYEDTYNTLKYASRAKKIRTTLKQN----- 353
             |:|||||.|||:|:||||||.:|||:|.||.|...:.:|.||||||:||:.|:..:|.|
  Fly   311 LHVPYRDSKLTRLLQDSLGGNSQTLMIACVSPSDRDFMETLNTLKYANRARNIKNKVKINQDQSS 375

  Fly   354 ----------------VLKSK-------------MPTEFYVKKIDEVVAENERLKERNKALEAKA 389
                            :|:.|             :...|...|:  :::|.:||::|.|:|::..
  Fly   376 RTISQLRREIAALQLELLEYKQGKLIVDCEGNTTISDTFNENKL--LLSEIKRLQQRLKSLQSTI 438

  Fly   390 TQLERAGNSGFDPLELKTWYSKIDAVYAAARQLQEHVLGMRSKIKNINYRQTLKKELEEFRKLMC 454
            ..|.:........|:|..|.|..::....|:.:.:::|       .|...||...|.||.||.|.
  Fly   439 ATLTQRNADLKTNLDLNKWTSDDNSDVEIAKVVGQYML-------EIEELQTKLIESEEHRKQME 496

  Fly   455 VDQRVCQEDFRRF--ANYMSTLTSQMEKYKEELPSWLSKMEIAYQDLESLKREV--NKSKAYQIL 515
            :.......:.:..  ::.::.....:|:.:|.|.| .|...|..|::.|.:.||  :.|:|.:::
  Fly   497 IKATTSPRNAKPVYDSDIITKAKKDLERERELLMS-RSLPGIQNQNVSSEETEVASSDSEAEEVV 560

  Fly   516 IVYVKYKDLELQLTKQNIFNNHVNAINQELVENLDL-------MRKSFRTACEVLNQTYDRLEDG 573
                  ||||       ..:|.:. :..:|:|.|:|       ||..:.   |.|:..|.::|:.
  Fly   561 ------KDLE-------AIDNDIE-MRTKLIEQLELTNSRYEQMRTHYE---EKLSVLYCKIENT 608

  Fly   574 QK-------------LTPEIEAV-------------FERLLRKMRFADSE--------------A 598
            ||             .||..:::             .:..:||::.|..|              .
  Fly   609 QKERDDVLANMTTSVSTPSKDSLKKVKTDYESKISHMQTEIRKLQNAQREHIRSKQQLKSHEVRI 673

  Fly   599 NTKMAEMNPL---AVPVALRSSAQ-----EEEEPTCSLTASAKKRQRQAAQSDDDLHLSME-DFD 654
            .|...|:|.|   .|.:..:.|.|     :||.......|...|.||:  |.:..|.|..: ...
  Fly   674 GTLRNELNELKFAKVKLMKKMSQQSNRHKQEESRKSKEIAQLLKEQRR--QKNAVLTLEAKVSAK 736

  Fly   655 SQDTESDSEELHRTFKRPRNLNETQVLGPCSSSSSSSTSSSSSARKA-----------LTAT--- 705
            .|..:..:||:....|..|..:..:  .|...:|..:|....|.|.|           |.|.
  Fly   737 EQILKRKTEEVIALRKSQRGKSGQR--APAHLTSKIATLDGFSTRSARHRWENLYRNILHAARNR 799

  Fly   706 --VTKPRTVQQRLV---SDLISDQNVRGGNEKIKKALLKSNHFTAQGLQRTLAAASLAKENVKYN 765
              :|:.....:||:   .||..:.|:....:...:...:.|..                :|:|.|
  Fly   800 QLITQLEKELERLILEREDLSRELNIMENGQTADRQTDEFNEV----------------DNLKTN 848

  Fly   766 ANYVRKS 772
            .:|::::
  Fly   849 ISYIQEN 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp67A	NP_001286999.1	KISc	8..353	CDD:214526	146/382 (38%)
		KISc_KIP3_like	8..346	CDD:276821	144/375 (38%)
Klp31E	NP_001162935.1	KISc_KIF4	12..364	CDD:276823	144/377 (38%)
		KISc	13..370	CDD:214526	146/382 (38%)
		KASH_CCD	409..589	CDD:291334	45/203 (22%)
		RasGAP	<685..750	CDD:295371	15/66 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437939
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940