Protein Alignment Klp67A and klp6

DIOPT Version :10

• Sequence 1: NP_523992.2
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_001342739.1
• Gene: klp6 / 2539700
• PomBaseID: SPBC1685.15C
• Length: 784
• Species: Schizosaccharomyces pombe
• Alignment Length: 886
• Identity: 255/886 - (28%)
• Similarity: 410/886 - (46%)
• Gaps: 199/886 - (22%)

  Fly     4 EQHTNIKVAVRVRPYNVREL-------EQKQ----------------------RSIIKVMDRSAL 39
            ::.::|.|||||||:..||.       :.|:                      |.|::|:|.:.|
pombe     2 KEGSSISVAVRVRPFTEREKGLLAETPKSKEFLGDGSLAVSNTSSNTFCTNGIRKIVRVLDDNVL 66

  Fly    40 LFDPDEEDDEFFFQGAKQP----YRDITKRMNKKLTMEFDRVFDIDNSNQDLFEECTAPLVDAVL 100
            :|||.||:.....|.:..|    :||:        ...|||:|..:.|.:|:::..|.||:|:||
pombe    67 IFDPPEENPLAKVQKSLLPAGKRFRDV--------RYAFDRLFGEEASQEDVYKGTTEPLLDSVL 123

  Fly   101 NGYNCSVFVYGATGAGKTFTMLGSEAHPGLTYLTMQDLFDKIQAQSDVRKFDVGVSYLEVYNEHV 165
            .|||.:||.|||||.|||.|:.|....||:.:|||:.|.|:::........|:.|||||:|||.:
pombe   124 QGYNATVFAYGATGCGKTHTISGRPDDPGIIFLTMRALLDRVEGLKRTMNVDISVSYLEIYNEKI 188

  Fly   166 MNLLT-------KSGPLKLRED-NNGVVVSGLCLTPIYSAEELLRMLMLGNSHRTQHPTDANAES 222
            .:||.       |...|.:.|| ...|.|.||......:.||::.:::.|||:||..||:|||.|
pombe   189 RDLLVQDPLSMEKPKSLNICEDAEQNVSVPGLSYFTPTNLEEVMEIIIRGNSNRTMSPTEANAVS 253

  Fly   223 SRSHAIFQVHIRIT------ERKTDTKRTVKL----SMIDLAGSERAASTKGIGVRFKEGASINK 277
            |||||:.|::|..|      :.:::::.:.|:    |.|||||||||::||..|.|..|||:||:
pombe   254 SRSHAVLQIYITQTPKSGEKQEESESQNSHKVRSVFSFIDLAGSERASATKNRGKRLVEGANINR 318

  Fly   278 SLLALGNCINKLADGLK--HIPYRDSNLTRILKDSLGGNCRTLMVANVSMSSLTYEDTYNTLKYA 340
            ||||||||||.|.:..:  |:|||||.|||:||.||||||||.|:..:|.||..|::|:|||||.
pombe   319 SLLALGNCINSLCEPRRRQHVPYRDSKLTRLLKFSLGGNCRTCMIVCISPSSEHYDETHNTLKYG 383

  Fly   341 SRAKKIRTTLKQNVLKSKMPTEFYVKKIDEVVAENERLKERNKALEAKATQLERAGNSGFDPLEL 405
            :|||.|:|.:.:||:........||:.|.| :.:...:.::..|.|:|...|.:         |:
pombe   384 NRAKNIKTKVSRNVVSVDRHVSEYVRTIYE-LRQKVSILQKRIAEESKQLALNK---------EV 438

  Fly   406 KTWYSKIDAVYAAARQLQEHVLGMRSKIKNI--NYRQTLKKELEEFRKLMCVDQRVCQEDFRRFA 468
            :    ||     ::|:::  :|..||.:||.  ..|...|..:|..|.|..::..:
pombe   439 R----KI-----SSREIK--MLDARSMLKNSFDGSRDLQKSLIEHVRTLRRIEDEI--------- 483

  Fly   469 NYMSTLTSQMEKYKEELPSWLSKME----IAYQDLESLKREVNKSKAY-QILIVYVKYKDLELQL 528
                |||..          |:|..:    ::..:::|:  |...:|.| |..::..|....|:..
pombe   484 ----TLTKM----------WISIAKESDAMSGHNIKSV--ETRLAKLYDQRSLITAKVNPEEICK 532

  Fly   529 TKQNIFNNHVNAINQE--------LVENLDLMRKSFRTACEVLNQTYDRLEDGQKLTPEIEAVFE 585
            |.||..::.|::...|        |.:::||::..      :.||..|...:.:..:.....:.:
pombe   533 TFQNSISHIVSSFKGEGADMYADMLQDDVDLLKSI------IENQILDAKHESETFSSTSRKLIQ 591

  Fly   586 RLLRKMRFADSEA---NTKMAEMNPLAVPVALRSSAQEEEEPTCSLTASAKKRQRQAAQSDDDLH 647
            .|..........|   |..:|......|.:.       ..|||..:....:|.:...
pombe   592 NLFLLFPLLPGNAIDVNESLARAFDQLVGIV-------PSEPTIQVPNLIEKGKAPL-------- 641

  Fly   648 LSMEDFDSQDTESDSEELHRTFKRPRNLNETQVLGPCSSSSSSSTSSSSSARKALTATVTKPRTV 712
            |||                  |:.||           |.|...:.|.|.:||     .:.||...
pombe   642 LSM------------------FEIPR-----------SPSRFKARSPSKAAR-----VLKKPLKK 672

  Fly   713 QQRLVSDLISDQNV-------RGGNEKIKKALLKSNH-------FTAQGLQRTLAAASLAKENVK 763
            :.|. |::.:..:|       :....|::|:|.|.|.       ..::..:.:|.:.||.....|
pombe   673 RVRF-SEVPTTSSVPPVEIKNKDSKPKVEKSLDKHNMNNDRSFLVPSRDARNSLTSLSLHSNVAK 736

  Fly   764 YNANYVRKSPRALMAKALAGTSTLARKPLGSAS-KEPPLVK 803
            ..:::..|.|...::..:   :|..::|:...| ...||.|
pombe   737 NKSSHSSKWPTHTLSPII---TTALKQPVRRISLVSQPLQK 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp67A	NP_523992.2	KISc_KIP3_like	8..346	CDD:276821	163/390 (42%)
klp6	NP_001342739.1	KISc_KIP3_like	6..389	CDD:276821	163/390 (42%)
		COG2433	<390..>479	CDD:441980	25/109 (23%)