DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Klp67A and LOC100494536

DIOPT Version :9

Sequence 1:	NP_001286999.1	Gene:	Klp67A / 39068	FlyBaseID:	FBgn0004379	Length:	814	Species:	Drosophila melanogaster
Sequence 2:	XP_031749711.1	Gene:	LOC100494536 / 100494536	-ID:	-	Length:	901	Species:	Xenopus tropicalis

Alignment Length:	835	Identity:	235/835 - (28%)
Similarity:	375/835 - (44%)	Gaps:	177/835 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 QDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLGSEAHPGLTYLTMQDLFDKIQAQSDVR 149
            ::::...|..|::.|::|||.:||.||.||.|||:||||.::.||:...|:.|||..|:..|:..
Frog    39 EEVYVSTTKSLIEGVISGYNATVFAYGPTGTGKTYTMLGLDSEPGIYIRTLNDLFRAIEVSSNSL 103

  Fly   150 KFDVGVSYLEVYNEHVMNLLTKSGPLKLREDNNG-VVVSGLCLTPIYSAEELLRMLMLGNSHRTQ 213
            .:.|.:||||:|||.:.:||..:|.|:||||..| :.::|:......:|||::..|..||..|||
Frog   104 DYTVSMSYLEIYNEIIRDLLNPAGVLELREDAKGNIQIAGITEFSTSNAEEIMEFLRKGNKQRTQ 168

  Fly   214 HPTDANAESSRSHAIFQVHIRITERKTDTKRTV---KLSMIDLAGSERAASTKGIGVRFKEGASI 275
            .||.||..||||||:.||.::...:..|....|   ||.|:||||||||:.|:..|.|.||||.|
Frog   169 EPTAANRTSSRSHAVLQVTVKQKSKGKDINEEVCIGKLFMVDLAGSERASQTRHCGKRMKEGAHI 233

  Fly   276 NKSLLALGNCINKLAD---GLKHIPYRDSNLTRILKDSLGGNCRTLMVANVSMSSLTYEDTYNTL 337
            |.||||||||||.|::   ...|:.:|||.|||:||||||||.||:|:|::|.:|.::|::..||
Frog   234 NLSLLALGNCINALSEKGGNRTHVNFRDSKLTRLLKDSLGGNSRTVMIAHISPASTSFEESRATL 298

  Fly   338 KYASRAKKIRTTLKQNVLKSKMPTEFYVKKIDEVVAENERLKERNKALE-AKATQLERAGN---- 397
            .||.|||.|:|.:|:|:.........|...|.::..|.|.|:|:.|..| .|..:.....|
Frog   299 IYAYRAKNIKTRVKRNLQNVSYHIAQYTSIISDLRKEIEHLEEKIKQQEREKKAERTNVSNIQGG 363

  Fly   398 -----SGFDPLELKTWYSKIDAVYAAARQLQEHVLGMRSKIKNINYRQTLKKELEEFRKLMCV-- 455
                 |.:...::.....::.:.:....:::..:|    :::|.|    ::..::..|.|:.:
Frog   364 VLGKASSYSREQMSILREQLISAFKEQMEMRRSLL----QLENTN----IELHIDTSRHLITIAD 420

  Fly   456 --------DQRVCQEDFR------RFAN------------------------YMSTLTSQMEK-- 480
                    |::..|:..|      |.|:                        .:|.|.::..|
Frog   421 WEQDRARHDKKPGQKIKRDKTAENRLADSTDEENEEEDGSSPEPHEVTVAREEISMLLAEQIKNA 485

  Fly   481 -YKEELPSWLSKMEIAYQDLESL-KREVNKSKAYQILIVYVKYKDLELQLTKQNIFNNHVNAINQ 543
             .|.||...||..::....||.| .::::..:..::|.:..:..:||::              |.
Frog   486 SLKAELEKRLSNTKLKASQLERLFPKQISSEEQQEVLRLLCRVHELEVE--------------NT 536

  Fly   544 EL------VENLDLMRKSF--------RTAC-EVLNQTYDRLEDGQKLTPEIEAVFERLLRKMRF 593
            ||      .||| |.:|.|        ||.| |::.|....:||.:...||   ..|||.:....
Frog   537 ELQAKALCKENL-LCQKDFVILHYQQHRTLCDEIIQQQQTLIEDYKIHVPE---SLERLYQVHSL 597

  Fly   594 ADSEANTKMAEMNPLAVPVALRS---SAQEEEEPTCSLTASAKKRQRQAAQSDDDLHLSMEDFDS 655
            ...:......:.....:...||.   |.:..:.|      :.|:.::..|:|....|
Frog   598 EVEKGTLNRLQQFQFVISNTLRDCLVSGESFQHP------NIKQLEKAVAESRKSFH-------- 648

  Fly   656 QDTESDSEELHRTFKRPRNLNETQVLGPCSSSSSSSTSSSSSARKALTATVTKPR-----TVQQR 715
                                ::.::..|.....|:|.|.:|.:..||..  |:|.     |....
Frog   649 --------------------SQAKLELPLVRIKSNSDSKTSGSTPALLQ--TRPNSSVSPTTFNL 691

  Fly   716 LVSDLISDQNVRGGNEKIKKALLKSNHFTAQ--------GLQR-------------TLAAASLAK 759
            |.:.....||...|.... .:||..|...||        ||..             :|.||....
Frog   692 LRTPTFQRQNTPAGKGNF-PSLLSPNPLEAQRRHSLSVKGLSPELLEEIAVETKSISLVAARRRL 755

  Fly   760 ENVKYNANYV---RKSPRA-----LMAKALAGTSTLARKPLGSASKEPPLVKFNR 806
            ..::..::::   ||||.:     ||.||::..:.||...|.:.....| .||:|
Frog   756 RILRSESSFLVDERKSPTSLDPSPLMKKAVSNDNILAALQLKTEKSFFP-SKFHR 809

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klp67A	NP_001286999.1	KISc	8..353	CDD:214526	131/274 (48%)
Klp67A	NP_001286999.1	KISc_KIP3_like	8..346	CDD:276821	128/267 (48%)
LOC100494536	XP_031749711.1	Motor_domain	<39..307	CDD:419868	128/267 (48%)
LOC100494536	XP_031749711.1	Smc	291..>609	CDD:224117	68/343 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000448
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000