Protein Alignment Klp67A and kif18b

DIOPT Version :9

• Sequence 1: NP_001286999.1
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_002939283.3
• Gene: kif18b / 100490953
• XenbaseID: XB-GENE-5960389
• Length: 872
• Species: Xenopus tropicalis
• Alignment Length: 892
• Identity: 303/892 - (33%)
• Similarity: 442/892 - (49%)
• Gaps: 144/892 - (16%)

  Fly     3 SEQHTNIKVAVRVRPYNVRELEQKQRSIIKVMDRSALLFDPDEEDDEFFFQGAKQPYRDITKRMN 67
            |.:..|:.|.|||||.|.||.|....::::|:|.:.|:|||||.:....|...:.  .|..||..
 Frog     7 STEEGNVSVVVRVRPPNQREQEGNHHAVVQVVDHNMLVFDPDEPETTGVFSSLRG--NDGPKRKG 69

  Fly    68 KKLTMEFDRVFDIDNSNQDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLGSEAHPGLTY 132
            |.:...|||:|..::..||:||..|..::|.||||||||||.|||||||||.|||||||.||:.|
 Frog    70 KDMKFIFDRIFGENSRQQDVFEHTTKEILDGVLNGYNCSVFAYGATGAGKTHTMLGSEADPGVMY 134

  Fly   133 LTMQDLFDKIQAQSDVRKFDVGVSYLEVYNEHVMNLLTKSGPLKLRED-NNGVVVSGLCLTPIYS 196
            |||.:|:.:|:|..:.:..:|.:||||||||.:.:||...|.|.:||| ..||||.||......|
 Frog   135 LTMVELYRRIEAIKEEKSCEVLISYLEVYNEQIQDLLEPRGSLAIREDPQKGVVVQGLSFHQPKS 199

  Fly   197 AEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRITERKTDTK---RTVKLSMIDLAGSER 258
            |::||:||..||.:||||||||||.||.|||:||::::..:|.....   |..|:|:||||||||
 Frog   200 ADQLLQMLASGNLNRTQHPTDANASSSHSHAVFQIYVKQQDRTVSISQDVRVAKMSLIDLAGSER 264

  Fly   259 AASTKGIGVRFKEGASINKSLLALGNCINKLADGLK---HIPYRDSNLTRILKDSLGGNCRTLMV 320
            |::|...|.|.:|||:||:|||||.|.||.|||...   |||||||.|||:||||:||||||:|:
 Frog   265 ASTTNAKGERLREGANINRSLLALINVINALADAKSKKAHIPYRDSKLTRLLKDSIGGNCRTVMI 329

  Fly   321 ANVSMSSLTYEDTYNTLKYASRAKKIRTTLKQNVLKSKMPTEFYVKKIDEVVAENERLKERNKAL 385
            |.:|.|:|:|:|||||||||:|||:|:.::|.||:........|....:|:.||...|:|:.:..
 Frog   330 AAISPSALSYDDTYNTLKYANRAKEIKLSMKSNVINLDCHISKYAAVCEELKAEVAELREKLRFY 394

  Fly   386 EAK--------------ATQLERAGNS-------GFDPLELKTWYSKIDAVYAAARQLQEHVLGM 429
            |.|              .|...|..:|       |...|.|.|          ::.|.|:|
 Frog   395 EMKEQPDDDTSDNSLQDKTSPRREEHSDLGSPEQGSGALLLST----------SSCQSQDH---- 445

  Fly   430 RSKIKNINYRQTLKKEL------EEFRKLMCVDQRVCQEDFRRFANYMSTLTSQMEKYKEELP-- 486
              |...:|.|:..:..|      ||..|..|:.:.:..:...|.   :::|.:.:.|..|.|.
 Frog   446 --KPAEMNPRKWDQVPLNCSLGREELEKNPCLHEALKDDAAERL---VTSLLNFVRKQCEILKLA 505

  Fly   487 -SWLSKMEIAYQDLESLKREVNKSKAYQILIVYVKYKDLELQLTKQNIFNNHVNAINQELVENLD 550
             .:..::|...:.||.|.....|:.|.:     |..|:   |:|:::....|.   .||.|....
 Frog   506 GLYTPELEDELRQLEGLALRGQKATAEK-----VTEKE---QVTEEHEMETHK---EQEEVPQTP 559

  Fly   551 LMRK-SFRTACEVLNQTYDRLEDGQKLTPEIEAVFERLLRKMRFADSEANTKMAEMNPLAVPVAL 614
            |:.. .|....||:.   |.:...:|..|          .|...||...:...:..:|: |||..
 Frog   560 LVEDVVFDIKEEVIE---DPVPPARKRKP----------GKRYRADILPDNSPSLRSPI-VPVKR 610

  Fly   615 RSSAQEEEEPTCSLTASAK-------KRQRQAA----------QSDDDLHLSMEDFDSQD----T 658
            |..|  ...||.:..|...       ||.|:::          .|.:.|..:.:|..||.    |
 Frog   611 RREA--TNTPTKARLAGVPSTPEVQVKRPRKSSIPSRCRVSLRSSLNLLPSNAKDIASQPPSLCT 673

  Fly   659 ESDSEELH-RTFKRPRNLNETQVLGPCSSSSSS-------STSSSSSARKALTATVTKPRTVQQR 715
            ...:.::. :|..:.|....|..:..|:|..::       :|:...|......:.:.|..|..
 Frog   674 PKQTAKIQSQTVTKSRMPLGTSAIQNCASVPAAALAPRDMNTTFDLSEEGCFVSEMDKTVTFG-- 736

  Fly   716 LVSDLISDQNVRGGNEKIKKALLKSNH---FTAQGL--------QRTLAAASLAKENVKYNANYV 769
             .||....:||...|  |.....||:.   |:.:||        |.|.||.|.:.:.
 Frog   737 -TSDFPGWENVPIHN--IDTTFGKSSDVAVFSVKGLSVNHMNANQMTSAAKSYSHKR-------- 790

  Fly   770 RKSPRALMAKALAGT---STLARKPLGSA--SKEPPLVKFNRAASFR 811
            |:|..:.|::|..||   |.:||..:.:.  |::||.:..:..:|.|
 Frog   791 RRSSSSSMSRAGKGTLAQSRIARLQMSTVKKSQQPPTISESICSSPR 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp67A	NP_001286999.1	KISc	8..353	CDD:214526	188/351 (54%)
		KISc_KIP3_like	8..346	CDD:276821	186/344 (54%)
kif18b	XP_002939283.3	KISc_KIP3_like	23..355	CDD:276821	179/333 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	351	1.000	Domainoid score	I1009
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	386	1.000	Inparanoid score	I1977
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D310221at33208
OrthoFinder	1	1.000	-	-		FOG0000448
OrthoInspector	1	1.000	-	-		otm47861
Panther	1	1.100	-	-	O	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1854
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.070