Protein Alignment Klp67A and kif13a

DIOPT Version :10

• Sequence 1: NP_523992.2
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_002932725.3
• Gene: kif13a / 100490129
• XenbaseID: XB-GENE-1010803
• Length: 1967
• Species: Xenopus tropicalis
• Alignment Length: 843
• Identity: 224/843 - (26%)
• Similarity: 348/843 - (41%)
• Gaps: 232/843 - (27%)

  Fly     7 TNIKVAVRVRPYNVRELEQKQRSIIKVMDRSALLFDPDEEDDEFFFQGAKQPYRDITKRMNKKLT 71
            :.:.|||||||.|.|||:...:.::::.....:|..|.        ..|||.    ..|...|:
 Frog     4 SKVLVAVRVRPMNRRELDLNTKCVVEMEGNQTILQTPP--------ANAKQG----ESRKPPKV- 55

  Fly    72 MEFDRVF-DIDNSN------QDLFEECTAP-LVDAVLNGYNCSVFVYGATGAGKTFTMLGSEAHP 128
            ..||..| .:|.||      |:...:|... ::|....|||..:|.||.||:||:|:|:|:...|
 Frog    56 FAFDYCFWSMDESNTPKYAGQEAVFKCLGEGILDNAFQGYNACIFAYGQTGSGKSFSMMGTADQP 120

  Fly   129 GLTYLTMQDLFDKI-QAQSDVRKFDVGVSYLEVYNEHVMNLLTKSG---PLKLREDN-NGVVVSG 188
            ||.......||.:. :.:||.:.|.|.|||:|:|||.|.:||...|   .||:||.. .|..|.|
 Frog   121 GLIPRLCCALFQRASEEESDSQSFKVEVSYMEIYNEKVRDLLDPKGNRHSLKVREHKVLGPYVDG 185

  Fly   189 LCLTPIYSAEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRIT----ERKTDTKRTVKLS 249
            |....:.:.|::..::..||..||...|:.|.|||||||:|.:.:..|    :.....:|..|:|
 Frog   186 LSQLAVTNFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFSIIVTQTLYDHQSGNSGERVSKVS 250

  Fly   250 MIDLAGSERAASTKGIGVRFKEGASINKSLLALGNCINKLADGL------KHIPYRDSNLTRILK 308
            ::|||||||.:.|...|.|.|||::|||||..||..|:.|||..      |.:|||||.||.:||
 Frog   251 LVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKNKFVPYRDSVLTWLLK 315

  Fly   309 DSLGGNCRTLMVANVSMSSLTYEDTYNTLKYASRAKKI--------------------------- 346
            |:||||.:|.|:|.:|.::..||:|.:||:||.|||:|
 Frog   316 DNLGGNSKTAMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNARVIRELREEVEKLKE 380

  Fly   347 ----RTTLKQNVLKSKM-PTEFYVKKI----DEVVAENERLKE-RNKALEAKATQLERAG----- 396
                ..::|...||.|: .:|..::::    :|.:.:.|.:.: |.:.||:....||.:|
 Frog   381 QLSQAESMKAPELKEKLEESEKLIRELTITWEEKLRKTEEIAQGRQRQLESMGISLESSGIKVGD 445

  Fly   397 ------NSGFDPL--ELKTWY----SKIDAVYAAARQL------QEHVL---------------- 427
                  |...||.  ||..:|    ::|.|..:...||      |||.:
 Frog   446 DKCYLVNLNADPALNELLVYYLKGHNRIGADTSQDIQLFGIGIQQEHCVIHVASDGDTYLIPKEN 510

  Fly   428 ------------------GMRSKIKNINY-RQTLKKE-----LEEFRKLMCVDQRVCQE------ 462
                              |.|....|.:| |..|.|.     |:||.|     :..|.|
 Frog   511 ARTCVNGTLVCEQTPLWHGDRILWGNNHYFRLNLPKRKRKDWLKEFEK-----EAGCSETDLDAA 570

  Fly   463 -----------DFRRFANYMSTLTSQ---------MEK-YKEELPSWLSKMEIAYQ-DLESLKRE 505
                       :|.:....|..|.|.         :|| |.||..:.|.:..:.|: :||.|:.:
 Frog   571 SEASSEPDYNYEFAQMEVIMKALNSNDPVHNVVQVLEKQYLEEKRTALEEQRLMYERELEQLRHQ 635

  Fly   506 VNKSKAYQILIVYVKYKDLELQLTKQNIFNNHVNAINQELVENLDLMRKSFRTACEVLNQTYDRL 570
            ::..:.:|                                 .:.:.:....:||.:.:|...:
 Frog   636 LSPDRHHQ---------------------------------HSTERLSYGSQTAQQKMNMWAE-- 665

  Fly   571 EDGQKLTPEIEAVFERLLRKMRFADSEANTKMAEMNPLA--------------VPVALRSSAQEE 621
                    |.:.:|.:.|.|:|....:|||.:.|.|.||              :| |:..||..:
 Frog   666 --------ERDELFRQSLSKLREQIVKANTLVREANFLAEEMNKCTDYQVTLQIP-AVNLSANRK 721

  Fly   622 -----EEPTCSLTASAKKRQRQAAQSDDDLHLSMEDFDSQDTESDSEELHRTFKRPRNLNETQ 679
                 .||...:....:..|....:..::..:.|.|...:..|...|....::|:.....|.|
 Frog   722 RGAIVSEPAIQVRRRCRGTQIWTIEKLENKLIDMRDAYQEWKEKPQENKRVSYKKGNPFYEAQ 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp67A	NP_523992.2	KISc_KIP3_like	8..346	CDD:276821	140/360 (39%)
kif13a	XP_002932725.3	KISc_KIF1A_KIF1B	4..360	CDD:276816	141/368 (38%)
		Kinesin_assoc	357..468	CDD:465047	19/110 (17%)
		FHA_KIF13A	447..555	CDD:438781	21/107 (20%)
		SMC_prok_B	<553..>765	CDD:274008	45/260 (17%)
		KIF1B	748..792	CDD:463574	7/37 (19%)
		bMERB_dom	<1102..1146	CDD:463467
		DUF3694	<1224..1279	CDD:463599
		CAP_GLY	1836..1900	CDD:460154