Protein Alignment Klp67A and kif19

DIOPT Version :9

• Sequence 1: NP_001286999.1
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_031750317.1
• Gene: kif19 / 100145702
• XenbaseID: XB-GENE-5954822
• Length: 1001
• Species: Xenopus tropicalis
• Alignment Length: 860
• Identity: 246/860 - (28%)
• Similarity: 406/860 - (47%)
• Gaps: 162/860 - (18%)

  Fly     9 IKVAVRVRPYNVRELEQKQRSII-KVMDRSALLFDPDEEDDEFFFQGAKQPYRDITKRMNKKLTM 72
            :.||:|:||.|..||.:....|. ||.::..:|.||.|:.|:.           :....:::.:.
 Frog    12 LTVALRIRPINEAELGEGATIIAHKVDEQMVVLMDPMEDPDDV-----------LRANRSREKSY 65

  Fly    73 EFDRVFDIDNSNQDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLGSEAHPGLTYLTMQD 137
            .||..||...:...::...|..|::.|::|||.:||.||.||.|||:||||::..||:...|:.|
 Frog    66 MFDVAFDYTATQDTVYRLTTKGLIEGVISGYNATVFAYGPTGCGKTYTMLGTDWEPGIYIRTLND 130

  Fly   138 LFDKIQAQSDVRKFDVGVSYLEVYNEHVMNLLTKS-GPLKLREDNNGVV-VSGLCLTPIYSAEEL 200
            ||..|:..||..:::|.:||:|:|||.:.:||..| |.|.||||:.||: |:|:......:|:|:
 Frog   131 LFKAIEETSDDMEYEVLMSYMEIYNEMIRDLLNPSLGYLDLREDSKGVIQVAGITEVSTINAKEI 195

  Fly   201 LRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRITERK---TDTKRTVKLSMIDLAGSERAAST 262
            :::||.||..|||.||.||..|||||||.||.:|...|.   |...|..:|.||||||||||:.|
 Frog   196 MQLLMKGNKQRTQEPTAANKTSSRSHAILQVTVRQKSRVKNITQEVRVGRLFMIDLAGSERASQT 260

  Fly   263 KGIGVRFKEGASINKSLLALGNCINKLAD--GLKHIPYRDSNLTRILKDSLGGNCRTLMVANVSM 325
            :..|.|.||||.||:||||||||||.|::  |.|::.||||.|||:||||||||.||:|:|::|.
 Frog   261 QNRGQRMKEGAHINRSLLALGNCINALSERGGNKYVNYRDSKLTRLLKDSLGGNSRTVMIAHISP 325

  Fly   326 SSLTYEDTYNTLKYASRAKKIRTTLKQNVLKSKMPTEFYVKKIDEVVAENERLKERNKALEAKAT 390
            :|.::|::.|||.||.|||.|:|.:|:|:|........|...|.::..|.:||||:   ::.:..
 Frog   326 ASTSFEESRNTLTYADRAKNIKTRVKRNLLNVSYHIAQYTSIISDLRKEIQRLKEK---IDEQGL 387

  Fly   391 QLERAGNSGFDPLELKTWYSKIDAVYAAARQLQEHVLGMRSKIKNINYRQTLKKELEEFRKLMCV 455
            :..|:..|....::.:..............||:|.:      |:....:..::::|.|.......
 Frog   388 KQLRSEKSDIRNIQAEVQLHSSPYGRHEMEQLKEQL------IRAFREQMDIRRQLMEIENSSME 446

  Fly   456 DQRVCQEDFRRFANYMSTLTSQMEKYKEEL-------------------------PSWLS----- 490
            .|......|...|::......:..|:|:||                         |..::
 Frog   447 MQMETSRHFLIIADWEQEKARRARKWKDELRKETYGKDDSEKDSDTGDEQSDIIEPPEVTTARET 511

  Fly   491 ----------------KMEIAYQDL--------ESLKREVNKSKAYQILIVYVKYKDLELQLTKQ 531
                            ::|..::|:        |:|.:.::.....:||.:..|..:||::.|:
 Frog   512 IQILEGDQSKLRRQKLELEKRFRDIRQRARRLEEALPKRISSEDQREILSLLCKVHELEIENTE- 575

  Fly   532 NIFNNHV----NAINQE--LVENLDLMRKSFRTAC-EVLNQTYDRLEDGQKLTP-EIEAVFERLL 588
              ..:|.    |.|.|:  :|:..:    ..|:.| |::.|....:.|.....| ::|.::|...
 Frog   576 --MQSHALLKDNMIRQKNHMVQRFE----QHRSLCDEIIKQQRRIIYDHNLTVPHQLEDLYELYF 634

  Fly   589 RKMRFADSEANTKMAEMNPLAVPVALRSSAQEEEEPTCSLTASAKKRQRQAAQSDDDLHLSMEDF 653
            |::         :...::.:|| :||:.| |........|||   :...|...||.:   |:..|
 Frog   635 REL---------EEGVLDKVAV-LALKDS-QSSLPKIPYLTA---EENLQEPDSDQE---SVRTF 682

  Fly   654 DS-------------------QDTESDSEELHRTFKRPRNLNETQVLGPCS-------------- 685
            .|                   .:|:.|:.::.:|..|.|:|....|:.|..
 Frog   683 GSDNRNPIHRDSYKNLLPRILSETDGDTNKVFKTSPRARHLKNGAVVTPPPIHVNGIISKEYPPR 747

  Fly   686 ------SSSSSSTSSSSSARKALTATVTKPRTVQQRLVSDLISDQNVRGGNEKIKKALLKSNHFT 744
                  |...:|:..|:..:.|||..       ::|.:|..|....|:....:.:  :|:.:...
 Frog   748 DHLVNISGHINSSPDSTDTKVALTRK-------EKREISTSIQSIAVKAARRRSR--VLEGDRLQ 803

  Fly   745 AQGLQRTLAAASLAK 759
            ....:..|:..||::
 Frog   804 PMKERSNLSVHSLSE 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp67A	NP_001286999.1	KISc	8..353	CDD:214526	160/351 (46%)
		KISc_KIP3_like	8..346	CDD:276821	157/344 (46%)
kif19	XP_031750317.1	KISc_KIP3_like	11..346	CDD:276821	157/344 (46%)
		Smc	340..>577	CDD:224117	42/248 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000448
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000