DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRRF1 and Mrrf

DIOPT Version :9

Sequence 1:	NP_648302.2	Gene:	mRRF1 / 39067	FlyBaseID:	FBgn0035980	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_080698.1	Gene:	Mrrf / 67871	MGIID:	1915121	Length:	262	Species:	Mus musculus

Alignment Length:	239	Identity:	84/239 - (35%)
Similarity:	138/239 - (57%)	Gaps:	20/239 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RVSSSSPKLPLILQNNLENTKYLQVARDYAKGKDKKKEKGGKGKP-GKVEINEQQLREILNFDGL 80
            |..|:.|.:|:               |.:|..|.|.|   |||:| .:|.:|...:.:|::.:.:
Mouse    42 RQYSAYPAVPV---------------RHFATKKAKAK---GKGQPQARVTVNRALVEDIISLEEV 88

  Fly    81 NSQMQKSVMQMKEDFVKHLSLRSTSGAIDTLRIKVDGQEHELQELAQISRKNPKTIIVNMIGFPQ 145
            :..|:..|..:|::|.|.|::|:..|::|.:.:.....:..|.::.|||.|:|:.|:|||..||:
Mouse    89 DEDMKSVVEALKDNFNKTLNIRTAPGSLDHITVVTADGKVALNQIGQISMKSPQVILVNMASFPE 153

  Fly   146 TIPDVLKAIEKSGMNLNPQQDGTTLFIPIPKVTKEHRENLSKNAKALFVKYRDAIRGVQNEHIRK 210
            .....:|||.:|||||||:.:||.:.:||||||:||||.|.|.||....|.::.:|.|:...:.|
Mouse   154 CTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKENLRKVRTNAMNK 218

  Fly   211 LKKQPELGKDDAF-AAQAQVTAIADRFISEADKLLASKQKELLG 253
            |||..:...:|.. ..:.|::.:||..::|.|:.||:|.|||||
Mouse   219 LKKSKDKTSEDTIRLIEKQISQMADDTVAELDQHLAAKTKELLG 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRRF1	NP_648302.2	RRF	76..252	CDD:238288	65/176 (37%)
Mrrf	NP_080698.1	RRF	99..260	CDD:396363	62/160 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833369
Domainoid	1	1.000	124	1.000	Domainoid score	I5530
eggNOG	1	0.900	-	-		E1_COG0233
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12203
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4426
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62479
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003951
OrthoInspector	1	1.000	-	-		oto93406
orthoMCL	1	0.900	-	-		OOG6_101101
Panther	1	1.100	-	-	LDO	PTHR20982
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2772
SonicParanoid	1	1.000	-	-		X5763
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790