DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pdxk and pdxka

DIOPT Version :9

Sequence 1:	NP_996031.1	Gene:	Pdxk / 39066	FlyBaseID:	FBgn0085484	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	XP_021334450.1	Gene:	pdxka / 791775	ZFINID:	ZDB-GENE-030131-8376	Length:	340	Species:	Danio rerio

Alignment Length:	307	Identity:	152/307 - (49%)
Similarity:	204/307 - (66%)	Gaps:	17/307 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RVLSIQSHVVHGYVGNKVATYPLQLLGFDVDPLNSVQFSNHTGYKTFKGPVSNEKELATIFEGLE 75
            ||||:|||||.||||||.||:|||:|||:||.:|||||||||||:.:||.|....||..::||::
Zfish     4 RVLSVQSHVVRGYVGNKSATFPLQVLGFEVDTINSVQFSNHTGYEHWKGQVLTADELNVLYEGIK 68

  Fly    76 ENELLPLYSHLLTGYIGNPLFLRQVGHILKKLRQANPGLVYVCDPVMGDNGQLYVPKELLPVYRD 140
            .|: :..|.::||||..:..||..|..|:::|::|||.||||||||:||||.:|||:.|||:|||
Zfish    69 LND-VNHYDYVLTGYTRDYSFLDMVVDIVQELKRANPSLVYVCDPVLGDNGAMYVPENLLPIYRD 132

  Fly   141 EIIPLADIITPNQFEVELLTEKEVRSEAAVWEAMEWFHQRGIKTVVISSSDLGQP---GVLRAFL 202
            .::|.||||||||||.|||:.:::.||....|.|...|..|..||||:||||..|   ..|.|..
Zfish   133 RVVPAADIITPNQFEAELLSGRKIHSEKDAVEVMNLLHSMGPDTVVITSSDLPSPLGDQYLVALG 197

  Fly   203 SQQN--------GPRLAIDIPKQGGKDLVFTGTGDLFASLFLAHSHGSKDIANVFEKTIASLQAV 259
            ||:.        ..::.:|||:   .|.||.|||||||::.||.:|...|:....|||.:.|..|
Zfish   198 SQKKVRTDGSMVTQQIRMDIPR---VDAVFVGTGDLFAAMLLAWTHHHPDLKMACEKTASVLHHV 259

  Fly   260 IKRTV--ASLPNGGNGPVKAAERELKLVQSKTEIEQPQVLLKAQRLN 304
            ||||:  |....|.|.....|:.||::||||.:||.|.|:::..|::
Zfish   260 IKRTMTYAHEVAGPNRRPSPAQLELRMVQSKADIENPAVVVQCGRVD 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdxk	NP_996031.1	ribokinase_pfkB_like	11..303	CDD:294126	151/304 (50%)
pdxka	XP_021334450.1	ribokinase_pfkB_like	4..306	CDD:320807	152/305 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595243
Domainoid	1	1.000	154	1.000	Domainoid score	I4215
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2731
Inparanoid	1	1.050	270	1.000	Inparanoid score	I2983
OMA	1	1.010	-	-		QHG53875
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002400
OrthoInspector	1	1.000	-	-		otm24541
orthoMCL	1	0.900	-	-		OOG6_102185
Panther	1	1.100	-	-	O	PTHR10534
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1806
SonicParanoid	1	1.000	-	-		X1589
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.930