DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdxk and pdxkb

DIOPT Version :9

Sequence 1:	NP_996031.1	Gene:	Pdxk / 39066	FlyBaseID:	FBgn0085484	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001139058.1	Gene:	pdxkb / 564697	ZFINID:	ZDB-GENE-030616-521	Length:	306	Species:	Danio rerio

Alignment Length:	306	Identity:	145/306 - (47%)
Similarity:	204/306 - (66%)	Gaps:	22/306 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RVLSIQSHVVHGYVGNKVATYPLQLLGFDVDPLNSVQFSNHTGYKTFKGPVSNEKELATIFEGLE 75
            ||||||||||.||||||.|::|||::||:||.:|||||||||||..:||.|....||..::||::
Zfish     4 RVLSIQSHVVRGYVGNKSASFPLQVMGFEVDSINSVQFSNHTGYAHWKGQVLTADELHVLYEGIK 68

  Fly    76 ENELLPLYSHLLTGYIGNPLFLRQVGHILKKLRQANPGLVYVCDPVMGDNGQLYVPKELLPVYRD 140
            .|. :..|.::||||..:..||..|..|:::|::|||.||||||||:||:|.:|||:.|.|||::
Zfish    69 LNN-VNHYDYVLTGYNRDTSFLEMVADIVQELKRANPNLVYVCDPVLGDHGSMYVPQNLHPVYKN 132

  Fly   141 EIIPLADIITPNQFEVELLTEKEVRSEAAVWEAMEWFHQRGIKTVVISSSDLGQPGVLRAFL--- 202
            :::|:||||||||||.||||.|.:.:|....|.|:..|:.|..||||:|||| .|.:...||
Zfish   133 KVVPVADIITPNQFEAELLTGKNISTEKDAVEVMDLLHKMGPDTVVITSSDL-PPRLGDRFLVSL 196

  Fly   203 -SQ--------QNGPRLAIDIPKQGGKDLVFTGTGDLFASLFLAHSHG-SKDIANVFEKTIASLQ 257
             ||        :...|:.|::||   .|.||.|||||||::.||.:|. ..|:....|||.:.:.
Zfish   197 GSQRILMPDGTRTTQRIRIEVPK---VDAVFVGTGDLFAAMLLAWTHHYPTDLKTACEKTFSVMH 258

  Fly   258 AVIKRTVA---SLPNGGNGPVKAAERELKLVQSKTEIEQPQVLLKA 300
            .||:||::   .:...|..| ..::.||::||||.:||.|.::::|
Zfish   259 HVIQRTISYAHEMAGPGRRP-SPSQLELRMVQSKADIEDPAIVMEA 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdxk	NP_996031.1	ribokinase_pfkB_like	11..303	CDD:294126	145/306 (47%)
pdxkb	NP_001139058.1	ribokinase_pfkB_like	4..304	CDD:294126	145/306 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595244
Domainoid	1	1.000	154	1.000	Domainoid score	I4215
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2731
Inparanoid	1	1.050	270	1.000	Inparanoid score	I2983
OMA	1	1.010	-	-		QHG53875
OrthoDB	1	1.010	-	-		D1091630at2759
OrthoFinder	1	1.000	-	-		FOG0002400
OrthoInspector	1	1.000	-	-		otm24541
orthoMCL	1	0.900	-	-		OOG6_102185
Panther	1	1.100	-	-	LDO	PTHR10534
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1806
SonicParanoid	1	1.000	-	-		X1589
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940