DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UGP and YHL012W

DIOPT Version :9

Sequence 1:	NP_648300.3	Gene:	UGP / 39065	FlyBaseID:	FBgn0035978	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_011851.1	Gene:	YHL012W / 856374	SGDID:	S000001004	Length:	493	Species:	Saccharomyces cerevisiae

Alignment Length:	468	Identity:	152/468 - (32%)
Similarity:	245/468 - (52%)	Gaps:	57/468 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 EMGRFADLFGRFIQEEG-------------PALDWNKIQKLPENAVMNYSNLKSPKNEQNEIRNM 115
            |...|..:|.|::.|..             |.:|  ::.:|.:  :.||..|:.         .:
Yeast    45 EFSLFLHIFQRYVLENTSITHDLVCDKIRLPIID--EVVELDD--IKNYGLLEG---------KL 96

  Fly   116 LDKLVVIKLNGGLGTSMGCHGPKSVIPVRSDLTFLDLTVQQIEHLNKTYDANVPLVLMNSFNTDE 180
            |.||.::||.|.....:|...|  :..|::.::.||:.|:|.::||..|:::|||:.|.|..|:.
Yeast    97 LSKLAILKLTGKANPIIGKESP--LFEVKNGMSSLDVIVRQTQNLNVRYNSDVPLIFMTSLETES 159

  Fly   181 DTEKIVRK-YKGFRVQIHTFNQSCFPRISREHYLPVAKDFDVEK-DMEAWYPPGHGDFYDTFRNS 243
            .....:.: |...:|:..|..||.||:|.::..||:  |..:.. :.:.|||.|.|:..||...|
Yeast   160 QVSNFLEEHYSSSKVRWKTVVQSSFPQIDKDRLLPI--DLQINSHENDFWYPCGTGNLTDTLYFS 222

  Fly   244 GLLKKFIEEGREYCFLSNIDNLGATVDLNILNKLVGEERATTPVEFVMEVTDKTRADVKGGTLIQ 308
            |.|.|.|.:|:|..|:||:||||||.||||||.::.|:     :|:::||.::|......|.|..
Yeast   223 GELDKLIAQGKEILFVSNVDNLGATGDLNILNFIINEK-----IEYLVEVVERTANVSNTGVLAT 282

  Fly   309 MENKLRLLEIAQVPPEHVDDFKSVKTFKFFNTNNIWANLAAIDRVLRERTLNM-------EIIVN 366
            .:.|||.:....:..|      |..|.:..||||||.:|..:..::...:||:       :|...
Yeast   283 YKGKLRSVYYNCLSNE------SASTCRIVNTNNIWIDLKKLKVLIESNSLNLPIHSSESKITHK 341

  Fly   367 NKTLENGTRVIQLETAVGAAMKCFDGAIGINVPRSRFLPVKKSSDLLLVMSNLYTL-KNGSLVMS 430
            |:.:|    .:|.:|.:...:..|..:..:.|.|.||||::...||.|:.|.||.| .||:..:.
Yeast   342 NEEIE----CLQFKTQLVDCIAFFPNSRVLKVSRDRFLPLRTCKDLFLLKSTLYDLDSNGTFNLY 402

  Fly   431 PQRMFPTTPLVKLGENHFSKVKEFLGRFANIPDIIELDHLTVSGDVTFGRGVSLRGTVIIIANHG 495
            |.: |...|.:.||: .|:..:.|.....:||:|:||:||||.|:|.|||.::|:||||||.:..
Yeast   403 PLK-FGLLPSIDLGD-EFATYETFKIGVPDIPNILELEHLTVMGNVFFGRNITLKGTVIIICDEN 465

  Fly   496 DRIDIPAGAILEN 508
            |.|.:|.|:||||
Yeast   466 DVITVPDGSILEN 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UGP	NP_648300.3	UDPGP	68..485	CDD:396322	136/439 (31%)
YHL012W	NP_011851.1	QRI1	7..484	CDD:226734	152/468 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4284
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S342
OMA	1	1.010	-	-		QHG62878
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43511
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.830