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Protein Alignment UGP and UGP2

DIOPT Version :9

Sequence 1:	NP_648300.3	Gene:	UGP / 39065	FlyBaseID:	FBgn0035978	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_006750.3	Gene:	UGP2 / 7360	HGNCID:	12527	Length:	508	Species:	Homo sapiens

Alignment Length:	498	Identity:	315/498 - (63%)
Similarity:	392/498 - (78%)	Gaps:	10/498 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SKEFHEVTKRDALRLLEHDVDRLLETTEKARQPALKAEMGRFADLFGRFIQEEGPALDWNKIQKL 91
            :.:|.||.:::....::.:::::|.|.........|.::..|..||.||:||:||::||.|||:.
Human    17 ASQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRP 81

  Fly    92 PENAVMNYSNLKS---PKNEQNEIRNMLDKLVVIKLNGGLGTSMGCHGPKSVIPVRSDLTFLDLT 153
            ||:::..|..:|:   |.|    |.::|:||||:||||||||||||.||||:|.||::.||||||
Human    82 PEDSIQPYEKIKARGLPDN----ISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLT 142

  Fly   154 VQQIEHLNKTYDANVPLVLMNSFNTDEDTEKIVRKYKGFRVQIHTFNQSCFPRISREHYLPVAKD 218
            |||||||||||:.:|||||||||||||||:||::||...||:|:|||||.:|||::|..||||||
Human   143 VQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPVAKD 207

  Fly   219 FDVE-KDMEAWYPPGHGDFYDTFRNSGLLKKFIEEGREYCFLSNIDNLGATVDLNILNKLVGEER 282
            .... ::.||||||||||.|.:|.|||||..||.||:||.|:||||||||||||.|||.|:....
Human   208 VSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPN 272

  Fly   283 ATTPVEFVMEVTDKTRADVKGGTLIQMENKLRLLEIAQVPPEHVDDFKSVKTFKFFNTNNIWANL 347
            ... .|||||||:|||||||||||.|.|.||||:||||||..|||:||||..||.|||||:|.:|
Human   273 GKR-CEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISL 336

  Fly   348 AAIDRVLRERTLNMEIIVNNKTLENGTRVIQLETAVGAAMKCFDGAIGINVPRSRFLPVKKSSDL 412
            ||:.|:..:..::||||||.|||:.|..|||||||||||:|.|:.::|||||||||||||.:|||
Human   337 AAVKRLQEQNAIDMEIIVNAKTLDGGLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDL 401

  Fly   413 LLVMSNLYTLKNGSLVMSPQRMFPTTPLVKLGENHFSKVKEFLGRFANIPDIIELDHLTVSGDVT 477
            ||||||||:|..|||.||.:|.|||.||||||.: |:||:::|.||.:|||::||||||||||||
Human   402 LLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSS-FTKVQDYLRRFESIPDMLELDHLTVSGDVT 465

  Fly   478 FGRGVSLRGTVIIIANHGDRIDIPAGAILENKIVSGNMRILDH 520
            ||:.|||:||||||||||||||||.||:|||||||||:|||||
Human   466 FGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH 508

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.