DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UGP and mmy

DIOPT Version :9

Sequence 1:	NP_648300.3	Gene:	UGP / 39065	FlyBaseID:	FBgn0035978	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_609032.1	Gene:	mmy / 33903	FlyBaseID:	FBgn0259749	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	108/516 - (20%)
Similarity:	199/516 - (38%)	Gaps:	103/516 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ERAGVRGHQRA-------PSDSKEFHEVTKRDAL--RLLEHDVDRLL----ETTEKARQPALK-- 62
            ::..||.|:.|       |:.:|....:|...:|  ||.:...:.||    |.|...|...::
  Fly    11 QQTHVRRHRNAGGATSKSPNAAKTSPTMTDYLSLHSRLAQVGQEHLLKFWPELTNDERIDLVRDI 75

  Fly    63 -----AEMGRFADLFGRFIQEEGPALDWNKIQKLPENAVMNYSNLKSPKNEQNEIRNMLD----K 118
                 .|:..:.|.....:.|.|..|| :::|.|||..:::.:.....|.:......:|.    .
  Fly    76 EELNLDEIKLYFDRATVSMNENGIKLD-DRLQPLPEGKLISIARAPLEKLDAYRDEGLLQISNGH 139

  Fly   119 LVVIKLNGGLGTSMGCHGPKSV--IPVRSDLTFLDLTVQQIEHLNK-TYDAN-----VPLVLMNS 175
            :.|:.:.||.||.:|...||.:  :.::|..|...:..::|..|.: ..:||     :...:|.|
  Fly   140 VAVLLMAGGQGTRLGFDHPKGMYDVGLQSRKTLFRIQAERILKLEELAQEANGKRGHITWYIMTS 204

  Fly   176 FNTDEDTEK--IVRKYKGFRVQ-IHTFNQS---CFPRISREHYLPVAKDFDVEKDMEAWYPPGHG 234
            .:|.:.|..  :...:.|.:.: :..|.|.   ||....|     :..|   ||...|..|.|:|
  Fly   205 EHTVQPTYDYFVANNFFGLKAENVLLFEQGSLPCFEYDGR-----IILD---EKHRVARAPDGNG 261

  Fly   235 DFYDTFRNSGLLKKFIEEGREYCFLSNIDNLGATVDLNILNKLVGEERATTPVEFVMEVTDKTRA 299
            ..|...:..|:|....:.|..|....::||:...|...:......:|:|    :...:|.:|...
  Fly   262 GIYRAMKRQGILDDMQKRGVLYLHAHSVDNILIKVADPVFIGYCVQEKA----DCAAKVVEKAAP 322

  Fly   300 DVKGGTLIQMENKLRLLEIAQVPPEHVDDFKSVKTFK------------------FFNTNNIWAN 346
            :...|.:..::.|.:::|.:::         |.||.:                  ||::|.:...
  Fly   323 NEAVGVVAIVDGKYQVVEYSEI---------SAKTAEMRNSDGRLTFSAGNICNHFFSSNFLQKI 378

  Fly   347 LAAIDRVLRERTLNMEI-IVNN--KTL----ENGTRVIQLETAVGAAMKCFDGAIGINVPRSRFL 404
            .:..::.|:......:| .|:|  |.|    .||   |::|..|....:.....:.:.|||....
  Fly   379 GSTYEQELKLHVAKKKIPFVDNAGKRLTPDKPNG---IKIEKFVFDVFEFAQKFVAMEVPRDEEF 440

  Fly   405 PVKKSSDLL------LVMSNLYTLKN------GSLVMSPQRMFPTTPLVK-LGENHFSKVK 452
            ...|:||..      ...|:|:.|..      |.:|..  .:...:|.|. .|||..|.|:
  Fly   441 SALKNSDAAGKDCPSTARSDLHRLHKKYIEGAGGIVHG--EVCEISPFVTYAGENLASHVE 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UGP	NP_648300.3	UDPGP	68..485	CDD:396322	92/441 (21%)
mmy	NP_609032.1	P-loop_NTPase	<34..123	CDD:304359	19/89 (21%)
mmy	NP_609032.1	UDPGlcNAc_PPase	125..447	CDD:133036	68/345 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462256
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4284
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740