DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UGP and Ugp2

DIOPT Version :9

Sequence 1:	NP_648300.3	Gene:	UGP / 39065	FlyBaseID:	FBgn0035978	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001019914.1	Gene:	Ugp2 / 289827	RGDID:	1310210	Length:	508	Species:	Rattus norvegicus

Alignment Length:	498	Identity:	315/498 - (63%)
Similarity:	392/498 - (78%)	Gaps:	10/498 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SKEFHEVTKRDALRLLEHDVDRLLETTEKARQPALKAEMGRFADLFGRFIQEEGPALDWNKIQKL 91
            :.:|.||..::....::.:::::|.|.........|.::..|..||.||:||:||::||.|||:.
  Rat    17 ASQFQEVILQELELSVKKELEKILTTATSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRP 81

  Fly    92 PENAVMNYSNLKS---PKNEQNEIRNMLDKLVVIKLNGGLGTSMGCHGPKSVIPVRSDLTFLDLT 153
            ||:::..|..:|:   |.|    |.::|:||||:||||||||||||.||||:|.||::.||||||
  Rat    82 PEDSIQPYEKIKARGLPDN----ISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLT 142

  Fly   154 VQQIEHLNKTYDANVPLVLMNSFNTDEDTEKIVRKYKGFRVQIHTFNQSCFPRISREHYLPVAKD 218
            |||||||||||:.:|||||||||||||||:||::||...||:|:|||||.:|||::|..||:|||
  Rat   143 VQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPIAKD 207

  Fly   219 FDVE-KDMEAWYPPGHGDFYDTFRNSGLLKKFIEEGREYCFLSNIDNLGATVDLNILNKLVGEER 282
            .... ::.||||||||||.|.:|.|||||..|||||:||.|:||||||||||||.|||.|:....
  Rat   208 VSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIEEGKEYIFVSNIDNLGATVDLYILNHLMNPPN 272

  Fly   283 ATTPVEFVMEVTDKTRADVKGGTLIQMENKLRLLEIAQVPPEHVDDFKSVKTFKFFNTNNIWANL 347
            ... .|||||||:|||||||||||.|.|.||||:||||||..|||:||||..||.|||||:|.:|
  Rat   273 GKR-CEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISL 336

  Fly   348 AAIDRVLRERTLNMEIIVNNKTLENGTRVIQLETAVGAAMKCFDGAIGINVPRSRFLPVKKSSDL 412
            ||:.|:..:..::||||||.|||:.|..|||||||||||:|.|:.::|||||||||||||.:|||
  Rat   337 AAVKRLQEQNAIDMEIIVNPKTLDGGLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDL 401

  Fly   413 LLVMSNLYTLKNGSLVMSPQRMFPTTPLVKLGENHFSKVKEFLGRFANIPDIIELDHLTVSGDVT 477
            ||||||||:|..|||.||.:|.|||.||||||.: |:||:::|.||.:|||::||||||||||||
  Rat   402 LLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSS-FTKVQDYLRRFESIPDMLELDHLTVSGDVT 465

  Fly   478 FGRGVSLRGTVIIIANHGDRIDIPAGAILENKIVSGNMRILDH 520
            ||:.|||:||||||||||||||||.||:|||||||||:|||||
  Rat   466 FGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UGP	NP_648300.3	UDPGP	68..485	CDD:396322	276/420 (66%)
Ugp2	NP_001019914.1	UDPGP	57..473	CDD:279967	276/421 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349372
Domainoid	1	1.000	541	1.000	Domainoid score	I255
eggNOG	1	0.900	-	-		E1_COG4284
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	615	1.000	Inparanoid score	I863
OMA	1	1.010	-	-		QHG62878
OrthoDB	1	1.010	-	-		D314629at33208
OrthoFinder	1	1.000	-	-		FOG0002950
OrthoInspector	1	1.000	-	-		oto96525
orthoMCL	1	0.900	-	-		OOG6_102276
Panther	1	1.100	-	-	LDO	PTHR43511
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1950
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770