DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UGP and SPCC794.10

DIOPT Version :9

Sequence 1:	NP_648300.3	Gene:	UGP / 39065	FlyBaseID:	FBgn0035978	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_587758.1	Gene:	SPCC794.10 / 2539585	PomBaseID:	SPCC794.10	Length:	499	Species:	Schizosaccharomyces pombe

Alignment Length:	509	Identity:	199/509 - (39%)
Similarity:	323/509 - (63%)	Gaps:	22/509 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 HQRAPSDSK---EFHEVTKRDALRLLEHDVDRLLETTEKARQPALKAEMGRFADLFGRFIQE--E 79
            |:|....|:   :|..|....:...:::::|:|:..:..:.:.....:|..|..|:.|::..  :
pombe     3 HRRIHFKSQSTLDFDSVAVSISASTMKNELDKLVLNSRVSDKKTFGIQMDNFFALYRRYLLHTVK 67

  Fly    80 GPALDWNKIQKLPENAVMNYSNLKSPKNEQNEIRNMLDKLVVIKLNGGLGTSMGCHGPKSVIPVR 144
            |...||:.|:.|....:::|.:|...||    ....|::|.|:|||||:|.::|.:.||::|.||
pombe    68 GYECDWDSIRPLGPEDMIDYGDLPLCKN----AGKYLNRLAVVKLNGGMGNALGVNYPKAMIEVR 128

  Fly   145 SDLTFLDLTVQQIEHLNKTYDANVPLVLMNSFNTDEDTEKIVRKYKGFRVQIHTFNQSCFPRISR 209
            .:.:||||:::|||:||:.||.:||.:||||::|:::|.|::|||.|.::.|.||.||.:||:..
pombe   129 DNQSFLDLSIRQIEYLNRRYDVSVPFILMNSYDTNDETCKVLRKYAGCKIDISTFEQSRYPRVFV 193

  Fly   210 EHYLPVAKDFDVEKDMEAWYPPGHGDFYDTFRNSGLLKKFIEEGREYCFLSNIDNLGATVDLNIL 274
            :..|||.|  .....:|.||||||||.:|...:||.:::.:.:|::|.|:||||||||:||||||
pombe   194 DSQLPVPK--AAPSPIEEWYPPGHGDIFDALVHSGTIERLLAQGKDYLFVSNIDNLGASVDLNIL 256

  Fly   275 NKLVGEERATTPVEFVMEVTDKTRADVKGGTLIQMENKLRLLEIAQVPPEHVDDFKSVKTFKFFN 339
            :.::..:     :|:.||:||||:||:|.|.|:..:..|||||..|||.:|.::|.|.|.||:.|
pombe   257 SHVIDNQ-----IEYSMEITDKTKADIKVGILVNQDGLLRLLETNQVPEQHREEFMSDKVFKYIN 316

  Fly   340 TNNIWANLAAIDRVLRERTLNMEIIVNNKTL---ENGTRVIQLETAVGAAMKCFDGAIGINVPRS 401
            |||:|..|.|:.||:..|.||::|:.|.:|:   ....|:|:..||:|:|:..|....||.|.|.
pombe   317 TNNVWLYLPAVKRVVENRELNLDIMPNIETVYYNNEPARIIEFTTAIGSAISQFKKTEGIRVSRP 381

  Fly   402 RFLPVKKSSDLLLVMSNLYTLKNGSLVMSPQRM-FPTTPLVKLGENHFSKVKEFLGRFANIPDII 465
            ||:.||.||||.||..:||.:.:|||.:...|: || .|:|:: .|.|..:.|...|...:|.:.
pombe   382 RFISVKNSSDLFLVRCDLYNVDHGSLKIEESRLGFP-PPVVRM-SNEFKDIAELFCRIPYMPSMK 444

  Fly   466 ELDHLTVSGDVTFGRGVSLRGTVIIIANHGDRIDIPAGAILENKIVSGNMRILD 519
            :|..|::||:|.|||.|.|:|.::|:|:....:.||:.|:|||.:|:||.:|::
pombe   445 DLVSLSISGNVYFGRNVILKGNIVIVASENTILCIPSNAVLENCVVTGNCKIME 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UGP	NP_648300.3	UDPGP	68..485	CDD:396322	177/422 (42%)
SPCC794.10	NP_587758.1	UDPGP	53..464	CDD:279967	177/423 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	437	1.000	Domainoid score	I79
eggNOG	1	0.900	-	-		E1_COG4284
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	490	1.000	Inparanoid score	I254
OMA	1	1.010	-	-		QHG62878
OrthoFinder	1	1.000	-	-		FOG0002950
OrthoInspector	1	1.000	-	-		otm47175
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43511
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1950
TreeFam	1	0.960	-	-
	10	9.930