DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UGP and SPCC1322.04

DIOPT Version :9

Sequence 1:	NP_648300.3	Gene:	UGP / 39065	FlyBaseID:	FBgn0035978	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_588132.1	Gene:	SPCC1322.04 / 2538877	PomBaseID:	SPCC1322.04	Length:	506	Species:	Schizosaccharomyces pombe

Alignment Length:	510	Identity:	253/510 - (49%)
Similarity:	352/510 - (69%)	Gaps:	20/510 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GHQRAPSDSK-EFHEVTKRDALRLLEHDVDRLLETT-EKARQPALKAEMGRFADLFGRFIQEE-- 79
            |.|.:.|.|. .|.......|...::::::.|..|. :...:.|.:.||..|..||.|::||:
pombe     9 GRQHSKSQSAFAFDNTATSIAASTMKNELNHLASTVKDPLAKKAFQKEMDNFFSLFSRYLQEDAR 73

  Fly    80 GPALDWNKIQKLPENAVMNYSNLKSPKNEQNEI-RNMLDKLVVIKLNGGLGTSMGCHGPKSVIPV 143
            |..::|:.::......|:.|..:    .|...: |:.|:||.|:||||||||:|||.||||:|.|
pombe    74 GSEINWDLVESPKPEQVVEYDTI----TEAGGLSRDYLNKLAVLKLNGGLGTTMGCVGPKSIIEV 134

  Fly   144 RSDLTFLDLTVQQIEHLNKTYDANVPLVLMNSFNTDEDTEKIVRKYKGFRVQIHTFNQSCFPRIS 208
            |...:||||:|:||||||:.|:.|||.||||||||||.|.|:::||:..::.|.|||||.:||:.
pombe   135 RDGNSFLDLSVRQIEHLNRKYNVNVPFVLMNSFNTDEATAKVIKKYEAHKIDILTFNQSRYPRVH 199

  Fly   209 REHYLPVAKDFDVEKDMEAWYPPGHGDFYDTFRNSGLLKKFIEEGREYCFLSNIDNLGATVDLNI 273
            :|..|||....|  ..::.||||||||.::...|||::...|.:|:||.|:||||||||.|||||
pombe   200 KETLLPVPHTAD--SAIDEWYPPGHGDVFEALTNSGIIDTLIAQGKEYLFVSNIDNLGAVVDLNI 262

  Fly   274 LNKLVGEERATTPVEFVMEVTDKTRADVKGGTLIQMENKLRLLEIAQVPPEHVDDFKSVKTFKFF 338
            ||.:|     .|..|::||:|:||:|||||||||..:..:||||||||||:||::|||:|.||:|
pombe   263 LNHMV-----ETNAEYLMELTNKTKADVKGGTLIDYDGNVRLLEIAQVPPQHVEEFKSIKKFKYF 322

  Fly   339 NTNNIWANLAAIDRVLRERTLNMEIIVNNKTLEN---GTRVIQLETAVGAAMKCFDGAIGINVPR 400
            ||||:|.:|.::.||:....|:||||.|.||:::   ...:||||||.|||::.|..|.|:||||
pombe   323 NTNNLWFHLPSVKRVVNNHELSMEIIPNKKTIKHKGENINIIQLETAAGAAIRHFKNAHGVNVPR 387

  Fly   401 SRFLPVKKSSDLLLVMSNLYTLKNGSLVMSPQRMFPTTPLVKLGENHFSKVKEFLGRFANIPDII 465
            .||||||..||||||.|:||::.:|.:.|:|:|...|.||||||. ||.||.:|.....:||.|:
pombe   388 RRFLPVKTCSDLLLVKSDLYSINHGQVEMNPRRFGGTAPLVKLGA-HFKKVADFSAHIPSIPKIL 451

  Fly   466 ELDHLTVSGDVTFGRGVSLRGTVIIIANHGDRIDIPAGAILENKIVSGNMRILDH 520
            ||||||::|||..||.|:|:|||||:|:..:|||||.|::|||.:::||:.||:|
pombe   452 ELDHLTITGDVNIGRNVTLKGTVIIVASDANRIDIPNGSVLENCVITGNLNILEH 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UGP	NP_648300.3	UDPGP	68..485	CDD:396322	221/422 (52%)
SPCC1322.04	NP_588132.1	UDPGP	59..471	CDD:279967	221/423 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	437	1.000	Domainoid score	I79
eggNOG	1	0.900	-	-		E1_COG4284
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4919
Inparanoid	1	1.050	490	1.000	Inparanoid score	I254
OMA	1	1.010	-	-		QHG62878
OrthoFinder	1	1.000	-	-		FOG0002950
OrthoInspector	1	1.000	-	-		otm47175
orthoMCL	1	0.900	-	-		OOG6_102276
Panther	1	1.100	-	-	LDO	PTHR43511
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1599
SonicParanoid	1	1.000	-	-		X1950
TreeFam	1	0.960	-	-
	14	13.860