back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UGP and Ugp2

DIOPT Version :10

Sequence 1:	NP_648300.3	Gene:	UGP / 39065	FlyBaseID:	FBgn0035978	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_647458.1	Gene:	Ugp2 / 216558	MGIID:	2183447	Length:	508	Species:	Mus musculus

Alignment Length:	498	Identity:	314/498 - (63%)
Similarity:	391/498 - (78%)	Gaps:	10/498 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SKEFHEVTKRDALRLLEHDVDRLLETTEKARQPALKAEMGRFADLFGRFIQEEGPALDWNKIQKL 91
            :.:|.||..::....::.:::::|.|.........|.::..|..||.||:||:||::||.|||:.
Mouse    17 ASQFQEVILQELELSVKKELEKILTTAASHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRP 81

  Fly    92 PENAVMNYSNLKS---PKNEQNEIRNMLDKLVVIKLNGGLGTSMGCHGPKSVIPVRSDLTFLDLT 153
            ||:::..|..:|:   |.|    |.::|:||||:||||||||||||.||||:|.||::.||||||
Mouse    82 PEDSIQPYEKIKARGLPDN----ISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLT 142

  Fly   154 VQQIEHLNKTYDANVPLVLMNSFNTDEDTEKIVRKYKGFRVQIHTFNQSCFPRISREHYLPVAKD 218
            |||||||||||:.:|||||||||||||||:||::||...||:|:|||||.:|||::|..||:|||
Mouse   143 VQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPIAKD 207

  Fly   219 FDVE-KDMEAWYPPGHGDFYDTFRNSGLLKKFIEEGREYCFLSNIDNLGATVDLNILNKLVGEER 282
            .... ::.||||||||||.|.:|.|||||..|||||:||.|:||||||||||||.|||.|:....
Mouse   208 VSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIEEGKEYIFVSNIDNLGATVDLYILNHLMNPPN 272

  Fly   283 ATTPVEFVMEVTDKTRADVKGGTLIQMENKLRLLEIAQVPPEHVDDFKSVKTFKFFNTNNIWANL 347
            ... .|||||||:|||||||||||.|.|.||||:||||||..|||:||||..||.|||||:|.:|
Mouse   273 GKR-CEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISL 336

  Fly   348 AAIDRVLRERTLNMEIIVNNKTLENGTRVIQLETAVGAAMKCFDGAIGINVPRSRFLPVKKSSDL 412
            .|:.|:..:..::||||||.|||:.|..|||||||||||:|.|:.::|||||||||||||.:|||
Mouse   337 GAVKRLQEQNAIDMEIIVNPKTLDGGLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDL 401

  Fly   413 LLVMSNLYTLKNGSLVMSPQRMFPTTPLVKLGENHFSKVKEFLGRFANIPDIIELDHLTVSGDVT 477
            ||||||||:|..|||.||.:|.|||.||||||.: |:||:::|.||.:|||::||||||||||||
Mouse   402 LLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSS-FTKVQDYLRRFESIPDMLELDHLTVSGDVT 465

  Fly   478 FGRGVSLRGTVIIIANHGDRIDIPAGAILENKIVSGNMRILDH 520
            ||:.|||:||||||||||||||||.||:|||||||||:|||||
Mouse   466 FGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH 508

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.