DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGRP-LF and PGRP-SC1a

DIOPT Version :9

Sequence 1:	NP_648299.3	Gene:	PGRP-LF / 39064	FlyBaseID:	FBgn0035977	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_610407.1	Gene:	PGRP-SC1a / 35859	FlyBaseID:	FBgn0043576	Length:	185	Species:	Drosophila melanogaster

Alignment Length:	199	Identity:	68/199 - (34%)
Similarity:	107/199 - (53%)	Gaps:	26/199 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 VILLMVVGLAAGYFMWMMSFSTHSPNKGLHILDRSEWLGEPPS-----GKYPHLKLPVSNIIIHH 88
            |.||:.|.:.:.|..           :|::::.::||.|....     |.|      :|..||||
  Fly     5 VALLLAVLVCSQYMA-----------QGVYVVSKAEWGGRGAKWTVGLGNY------LSYAIIHH 52

  Fly    89 TATEGCEQEDVCIYRMKTIQAFHMKSFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNGYGAISV 153
            ||...||....|...::::|.:||.|.||.|||||||:||||.:|.||||:..|.|...:...|:
  Fly    53 TAGSYCETRAQCNAVLQSVQNYHMDSLGWPDIGYNFLIGGDGNVYEGRGWNNMGAHAAEWNPYSI 117

  Fly   154 SIAFIGTF--VNMEPPARQIEAAKRLMDEGVRLHRLQPDYHIYAHRQLSPTESPGQKLFELMQNW 216
            .|:|:|.:  ..:||  ..|.||::|:::.|...:|...|.:|.|||:|.||.||..::..::.|
  Fly   118 GISFLGNYNWDTLEP--NMISAAQQLLNDAVNRGQLSSGYILYGHRQVSATECPGTHIWNEIRGW 180

  Fly   217 PRFT 220
            ..::
  Fly   181 SHWS 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LF	NP_648299.3	PGRP	57..199	CDD:128941	55/148 (37%)
PGRP-LF	NP_648299.3	PGRP	236..363	CDD:295442
PGRP-SC1a	NP_610407.1	PGRP	22..163	CDD:128941	55/148 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440267
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11022
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950