DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGRP-LF and Pglyrp1

DIOPT Version :9

Sequence 1:	NP_648299.3	Gene:	PGRP-LF / 39064	FlyBaseID:	FBgn0035977	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_033428.1	Gene:	Pglyrp1 / 21946	MGIID:	1345092	Length:	182	Species:	Mus musculus

Alignment Length:	201	Identity:	69/201 - (34%)
Similarity:	107/201 - (53%)	Gaps:	22/201 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LLYFCVILLMVVGLAAGYFMWMMSFSTHSPNKGLHILDRSEWLGEPP--SGKYPHLKLPVSNIII 86
            :|:.|. ||.::|||..     .||          |:.||||...|.  |.:..|   ||..::|
Mouse     1 MLFACA-LLALLGLATS-----CSF----------IVPRSEWRALPSECSSRLGH---PVRYVVI 46

  Fly    87 HHTATEGCEQEDVCIYRMKTIQAFHMKSFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNG-YGA 150
            .|||...|...|.|..:.:.:|.:|....||.|:.||||:|.||.:|.||||:|:|.|... :..
Mouse    47 SHTAGSFCNSPDSCEQQARNVQHYHKNELGWCDVAYNFLIGEDGHVYEGRGWNIKGDHTGPIWNP 111

  Fly   151 ISVSIAFIGTFVNMEPPARQIEAAKRLMDEGVRLHRLQPDYHIYAHRQLSPTESPGQKLFELMQN 215
            :|:.|.|:|.|::..|..|.:.||..|::.||....|:.:|.:..||.:..|.|||.:|::::|:
Mouse   112 MSIGITFMGNFMDRVPAKRALRAALNLLECGVSRGFLRSNYEVKGHRDVQSTLSPGDQLYQVIQS 176

  Fly   216 WPRFTQ 221
            |..:.:
Mouse   177 WEHYRE 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LF	NP_648299.3	PGRP	57..199	CDD:128941	53/144 (37%)
PGRP-LF	NP_648299.3	PGRP	236..363	CDD:295442
Pglyrp1	NP_033428.1	PGRP	20..160	CDD:128941	53/142 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842390
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5479
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6354
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.700