Protein Alignment PGRP-LF and PGLYRP3

DIOPT Version :10

• Sequence 1: NP_648299.3
• Gene: PGRP-LF / 39064
• FlyBaseID: FBgn0035977
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: XP_011507420.1
• Gene: PGLYRP3 / 114771
• HGNCID: 30014
• Length: 377
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 96/344 - (27%)
• Similarity: 151/344 - (43%)
• Gaps: 57/344 - (16%)

  Fly    42 FMWMMSFSTHSPNKGLHILDRSEWLGEPPSGKYPHLKLPVSNIIIHHTATEGCEQEDVCIYRMKT 106
            |:.:..|.....|....|:.|.|| |..|......|.|||:.||........|:|:.||...::.
Human    42 FVSISQFIHKGRNDTPTIVSRKEW-GARPLACRALLTLPVAYIITDQLPGMQCQQQSVCSQMLRG 105

  Fly   107 IQAFHMKSFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPARQI 171
            :|:..:.:.||.|:.||||||.||::|.|.||:|||.|..||..||:.|||.|..:...|....:
Human   106 LQSHSVYTIGWCDVAYNFLVGDDGRVYEGVGWNIQGLHTQGYNNISLGIAFFGNKIGSSPSPAAL 170

  Fly   172 EAAKRLMDEGVRLHRLQPDYHIYAHRQLSPTESPGQKLFELMQNWPRFTQDPTSLRLLSNETV-- 234
            .||:.|:...::...|.|.|       :.|.                         ||..||.
Human   171 SAAEGLISYAIQKGHLSPRY-------IQPL-------------------------LLKEETCLD 203

  Fly   235 ------------KIVTRPYWLAQPPIVPLTPLKLPIESVRFVATNTPSCFTQAECTFRVRLLQNW 287
                        .|:.|..|.|:....|  .:.||.:.|..:.|...||....:|...||.:|::
Human   204 PQHPVMPRKVCPNIIKRSAWEARETHCP--KMNLPAKYVIIIHTAGTSCTVSTDCQTVVRNIQSF 266

  Fly   288 HIESNGYKDINYNFVAAGDENIYEARGWDHSCEPPKDADELV--VAFIG------PSSSNKKIAL 344
            |:::..:.||.|:|:...|..:||..||..........:::.  :||||      |:::..:.|.
Human   267 HMDTRNFCDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFIGYFVEKPPNAAALEAAQ 331

  Fly   345 ELIKQGIKLGHISKNYSLI 363
            :||:..:..|:::.||.|:
Human   332 DLIQCAVVEGYLTPNYLLM 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LF	NP_648299.3	PGRP	57..199	CDD:128941	51/141 (36%)
		PGRP	236..363	CDD:470657	36/134 (27%)
PGLYRP3	XP_011507420.1	PGRP	57..195	CDD:128941	52/170 (31%)
		PGRP	215..355	CDD:128941	37/138 (27%)