Protein Alignment PGRP-LF and PGLYRP2

DIOPT Version :10

• Sequence 1: NP_648299.3
• Gene: PGRP-LF / 39064
• FlyBaseID: FBgn0035977
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001350475.1
• Gene: PGLYRP2 / 114770
• HGNCID: 30013
• Length: 634
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 72/205 - (35%)
• Similarity: 101/205 - (49%)
• Gaps: 30/205 - (14%)

  Fly    62 RSEWLGEPPSGKYPHLKLPVSNIIIHHTATEG--CEQEDVCIYRMKTIQAFHMKSFGWVDIGYNF 124
            |..|...|..|:...|:||:..:.:|||....  |.....|...|:::|.:|..:.||.||||:|
Human   385 RCRWGAAPYRGRPKLLQLPLGFLYVHHTYVPAPPCTDFTRCAANMRSMQRYHQDTQGWGDIGYSF 449

  Fly   125 LVGGDGQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPARQIEAAKRLMDE-----GVRL 184
            :||.||.:|.|||||..|.|..|:.:....:|.:|.:....|    .|||.|.:.:     .||.
Human   450 VVGSDGYVYEGRGWHWVGAHTLGHNSRGFGVAIVGNYTAALP----TEAALRTVRDTLPSCAVRA 510

  Fly   185 HRLQPDYHIYAHRQLSPTESPGQKLFELMQNWPRFTQDPTSLRLLSNETVKIVTRPYWLAQPPIV 249
            ..|:|||.:..||||..|:.||..||:|::.||.||  ..|||.|           ::.|:.|.|
Human   511 GLLRPDYALLGHRQLVRTDCPGDALFDLLRTWPHFT--AVSLRSL-----------HYTARRPSV 562

  Fly   250 ------PLTP 253
                  ||.|
Human   563 YTSSTRPLPP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LF	NP_648299.3	PGRP	57..199	CDD:128941	50/143 (35%)
		PGRP	236..363	CDD:470657	6/24 (25%)
PGLYRP2	NP_001350475.1	PGRP	380..525	CDD:128941	50/143 (35%)