DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGRP-LF and PGLYRP2

DIOPT Version :9

Sequence 1:	NP_648299.3	Gene:	PGRP-LF / 39064	FlyBaseID:	FBgn0035977	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001350475.1	Gene:	PGLYRP2 / 114770	HGNCID:	30013	Length:	634	Species:	Homo sapiens

Alignment Length:	205	Identity:	72/205 - (35%)
Similarity:	101/205 - (49%)	Gaps:	30/205 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 RSEWLGEPPSGKYPHLKLPVSNIIIHHTATEG--CEQEDVCIYRMKTIQAFHMKSFGWVDIGYNF 124
            |..|...|..|:...|:||:..:.:|||....  |.....|...|:::|.:|..:.||.||||:|
Human   385 RCRWGAAPYRGRPKLLQLPLGFLYVHHTYVPAPPCTDFTRCAANMRSMQRYHQDTQGWGDIGYSF 449

  Fly   125 LVGGDGQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPARQIEAAKRLMDE-----GVRL 184
            :||.||.:|.|||||..|.|..|:.:....:|.:|.:....|    .|||.|.:.:     .||.
Human   450 VVGSDGYVYEGRGWHWVGAHTLGHNSRGFGVAIVGNYTAALP----TEAALRTVRDTLPSCAVRA 510

  Fly   185 HRLQPDYHIYAHRQLSPTESPGQKLFELMQNWPRFTQDPTSLRLLSNETVKIVTRPYWLAQPPIV 249
            ..|:|||.:..||||..|:.||..||:|::.||.||  ..|||.|           ::.|:.|.|
Human   511 GLLRPDYALLGHRQLVRTDCPGDALFDLLRTWPHFT--AVSLRSL-----------HYTARRPSV 562

  Fly   250 ------PLTP 253
                  ||.|
Human   563 YTSSTRPLPP 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LF	NP_648299.3	PGRP	57..199	CDD:128941	50/143 (35%)
PGRP-LF	NP_648299.3	PGRP	236..363	CDD:295442	6/24 (25%)
PGLYRP2	NP_001350475.1	PGRP	380..525	CDD:128941	50/143 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152343
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850