Protein Alignment PGRP-LC and Pglyrp2

DIOPT Version :9

• Sequence 1: NP_001246693.1
• Gene: PGRP-LC / 39063
• FlyBaseID: FBgn0035976
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_006524773.1
• Gene: Pglyrp2 / 57757
• MGIID: 1928099
• Length: 544
• Species: Mus musculus
• Alignment Length: 513
• Identity: 116/513 - (22%)
• Similarity: 187/513 - (36%)
• Gaps: 128/513 - (24%)

  Fly   107 VSIDDNAIDSSS-IDSDSEAEAEDYTVQKL-----GHQVTYPPNSSHLRDLNQGLTVISRH---- 161
            |.:.:.:|.:|: |.|...:...:...|:|     .|..|.|...|...:|...::.:::|
Mouse    43 VPVTEASITASAWILSAKNSSTHNSLHQRLLLKAPSHNTTEPDPHSLSPELQALISEVAQHDVQN 107

  Fly   162 -------VAPGEAAV---PPPNPLEAGIVAKQILN----------------GNLAVATP------ 194
                   :||..:.|   |....||||:.|..:.|                .|:....|
Mouse   108 GREYGVVLAPDGSTVAVKPLLFGLEAGLQAHSVANLPSDCLAIPCDTGDTLANIRATWPGLMDAF 172

  Fly   195 ---TSPAGGATQGIGSIALTNSTDVTFGDKHFYEGPVTIQQFL------------IDNRDKWK-P 243
               :||..|||       |.|....|         |.|:.:.|            :.....|. |
Mouse   173 PNASSPDVGAT-------LPNDKAKT---------PTTVDRLLAITLAGDLGLTFLHRSQTWSPP 221

  Fly   244 GEGPAGGQD-----------NP-------AFNGGPSTNGSAPGSK-HEDPAQTPPICPFLPNTVG 289
            |.|..|..|           :|       ||..| :.:|:..|:. .:.|...||:...|....|
Mouse   222 GLGTEGCWDQLTAPRVFTLLDPQASRLTMAFLNG-ALDGALLGNHLSQIPRPHPPLSHLLREYYG 285

  Fly   290 RKAVTVTVVFVTLTFLLGIVLATTTNLFGKTLNQ---------SKIRDDDDYRQNIPINSTIDLD 345
             ..|....||.: .|......|.|:   ..||.|         .|:..:....|||   |...|.
Mouse   286 -AGVNGDPVFRS-NFRRQNGAALTS---APTLAQQVWEALVLLQKLEPEHLQLQNI---SQEQLA 342

  Fly   346 NIGGGLILRFVE----------RQQWLAQPPQKEIPDLELPVGLVIALPT--NSENCSTQAICVL 398
            .:.......|.|          |.:|.|.|.:.....|.||:|.:....|  .:..|:|...|..
Mouse   343 QVATLATKEFTEAFLGCPAIHPRCRWGAAPYRGHPTPLRLPLGFLYVHHTYVPAPPCTTFQSCAA 407

  Fly   399 RVRLLQTYDIESSQKCDIAYNFLIGGDGNVYVGRGWNKMGAHMNNINYDSQSLSFAYIGSFKTIQ 463
            .:|.:|.:..:..:..||.|:|::|.||.:|.||||:.:|||..  .|:|:....|::|::....
Mouse   408 DMRSMQRFHQDVRKWDDIGYSFVVGSDGYLYQGRGWHWVGAHTR--GYNSRGFGVAFVGNYTGSL 470

  Fly   464 PSAKQLSVTR-LLLERGVKLGKIAPSYRFTASSKLMPSVTDFKADALYASFANWTHWS 520
            |:...|:..| .|....::.|.:.|.|:.....:|:  :|....:||:.....|.|::
Mouse   471 PNEAALNTVRDALPSCAIRAGLLRPDYKLLGHRQLV--LTHCPGNALFNLLRTWPHFT 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LC	NP_001246693.1	PGRP	356..490	CDD:128941	40/146 (27%)
Pglyrp2	XP_006524773.1	PGRP	360..505	CDD:128941	40/146 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.880