DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGRP-LC and pglyrp6

DIOPT Version :9

Sequence 1:	NP_001246693.1	Gene:	PGRP-LC / 39063	FlyBaseID:	FBgn0035976	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001038687.2	Gene:	pglyrp6 / 571817	ZFINID:	ZDB-GENE-071227-2	Length:	498	Species:	Danio rerio

Alignment Length:	450	Identity:	97/450 - (21%)
Similarity:	160/450 - (35%)	Gaps:	121/450 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 DYTVQKLGH---QVTYPPN-SSHLRDLNQGLTVISRHVAPGEAAVPPPNPLEAGIVAKQILNG-N 188
            |.:.|.||.   ::|..|: :|::.:|      |:.||:         :..|.|:|.  .|:| |
Zfish   106 DLSQQLLGDAHPELTMDPSVASNIHEL------INHHVS---------DITEEGVVL--TLDGSN 153

  Fly   189 LAVATPTSPAGGATQGIGSIALTNSTDVTFGDKHFYEGPVTIQQFLIDNRDKWKPGEGP------ 247
            :|:|..........|.|....||.:.::.....|..:...:  ..|:..:..|...:.|
Zfish   154 VALAPLLLGLEAGLQSIDLYPLTLTENLLNSFVHHVQNQES--SALLGTKGYWDSIKSPRVYTLS 216

  Fly   248 -----------AGGQDNPAFNGGPSTNGSAP------------GSKHEDPAQTPPICPFLPNTVG 289
                       .||.|. ...|....:...|            ..|.:|.|         |..:.
Zfish   217 GLPSLATDALIIGGMDG-FILGSEMASSDHPEESLSSLLRSYYSQKLDDAA---------PRLIS 271

  Fly   290 RK-----------AVTVTVVFVTLTFLLGIVLATTTNLFGKTLNQSKIRDDDDYRQNIPINSTID 343
            :|           ::..|.|...||             ..:.|||.:.:..||.     :|...:
Zfish   272 QKRRMNFRNMADFSLMKTQVVRALT-------------VRRNLNQDERKKLDDV-----VNEGFE 318

  Fly   344 --------LDNIGGGLILRFVERQQWLAQPPQKEIPDLELPVGLVIALPT--NSENCSTQAICVL 398
                    ..||        :.|.||.|.........|.|||..:....|  .|:.|:|...|..
Zfish   319 EFVHVYAVCPNI--------ITRSQWGAASYIGSPSYLSLPVRYLFIHHTYQPSKPCTTFEQCAA 375

  Fly   399 RVRLLQTYDIESSQKCDIAYNFLIGGDGNVYVGRGWNKMGAHMNNINYDSQSLSFAYIGSFKTIQ 463
            .:|.:|.|..:|:...||.|:|:.|.|||:|.|||||.:|||  ...|:|......:||.:.:..
Zfish   376 EMRSMQRYHQQSNGWSDIGYSFVAGSDGNLYEGRGWNWVGAH--TYGYNSIGYGVCFIGDYTSTL 438

  Fly   464 PSAKQLSVTR----LLLERGVKLGKIAPSYRFTASSKLMPSVTDFKADALYASFANWTHW 519
            |::..:::.|    .....|   |:::.||......:  .:.|:...:.||.....|..:
Zfish   439 PASSAMNMVRYDFTYCATNG---GRLSKSYSLYGHRQ--AAATECPGNTLYRQIQTWERY 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LC	NP_001246693.1	PGRP	356..490	CDD:128941	43/139 (31%)
pglyrp6	NP_001038687.2	PGRP	328..472	CDD:128941	46/156 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920