DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PGRP-LA and PGRP-LF

DIOPT Version :9

Sequence 1:	NP_996026.1	Gene:	PGRP-LA / 39062	FlyBaseID:	FBgn0035975	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_648299.3	Gene:	PGRP-LF / 39064	FlyBaseID:	FBgn0035977	Length:	369	Species:	Drosophila melanogaster

Alignment Length:	220	Identity:	60/220 - (27%)
Similarity:	99/220 - (45%)	Gaps:	37/220 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 LITLILLVLATGLIVLYVELNRPKPELPSNKAIYFGNNYDHQTFPNLGNGHLVVDREQW----GA 191
            :|.|:::.||.|..:..:..:...|    ||.::                  ::||.:|    .:
  Fly    29 VILLMVVGLAAGYFMWMMSFSTHSP----NKGLH------------------ILDRSEWLGEPPS 71

  Fly   192 SKNSHGLTIPLKRPIPYVLITHIGVQSLPCDNIYKCSIKMRTIQDSAIAEKGLPDIQSNFYVSEE 256
            .|..|     ||.|:..::|.|...:.  |:....|..:|:|||...:...|..||..||.|..:
  Fly    72 GKYPH-----LKLPVSNIIIHHTATEG--CEQEDVCIYRMKTIQAFHMKSFGWVDIGYNFLVGGD 129

  Fly   257 GNIYVGRGW----DWANTYANQTLAITFMGDYGRFKPGPKQLEGVQFLLAHAVANRNIDVDYKLV 317
            |.|||||||    ...|.|...:::|.|:|.:...:|..:|:|..:.|:...|....:..||.:.
  Fly   130 GQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPARQIEAAKRLMDEGVRLHRLQPDYHIY 194

  Fly   318 AQNQTKVTRSPGAYVYQEIRNWPHF 342
            |..|...|.|||..:::.::|||.|
  Fly   195 AHRQLSPTESPGQKLFELMQNWPRF 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LA	NP_996026.1	PGRP	181..322	CDD:128941	43/148 (29%)
PGRP-LF	NP_648299.3	PGRP	57..199	CDD:128941	43/166 (26%)
PGRP-LF	NP_648299.3	PGRP	236..363	CDD:295442
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5479
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11022
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920