Protein Alignment CG4477 and TPSAB1

DIOPT Version :10

• Sequence 1: NP_648295.1
• Gene: CG4477 / 39058
• FlyBaseID: FBgn0035971
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 66/236 - (27%)
• Similarity: 107/236 - (45%)
• Gaps: 49/236 - (20%)

  Fly    70 HFCSGVILAPMFVMTSAHCLINKRRVLISSRVLLIVAGTLNRLKYIPNRTFVTPVTHIWL-PDSF 133
            |||.|.::.|.:|:|:|||:....:.|.:.||.|       |.:::..:..:.||:.|.: |..:
Human    57 HFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL-------REQHLYYQDQLLPVSRIIVHPQFY 114

  Fly   134 TMRNKQDFGLLKVKNPFPRNNEHISIARLP----VHPPLPGLKCKVMGWG------RMYKGGPLA 188
            |.:...|..||:::.|. ..:.|:....||    ..|  ||:.|.|.|||      |:....||.
Human   115 TAQIGADIALLELEEPV-NVSSHVHTVTLPPASETFP--PGMPCWVTGWGDVDNDERLPPPFPLK 176

  Fly   189 SYMLYIDVQVIDSEAC-AKWLRVPSVEHVCAVDSDDL------------TAQQPCGGDWGAPML- 239
            .    :.|.::::..| ||:       |:.|...||:            |.:..|.||.|.|::
Human   177 Q----VKVPIMENHICDAKY-------HLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVC 230

  Fly   240 -HNGT--VYGIVTILAGCGVSHLPSLYTNVHSNANWIHEKI 277
             .|||  ..|:|:...||...:.|.:||.|....:|||..:
Human   231 KVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4477	NP_648295.1	Tryp_SPc	55..276	CDD:238113	66/233 (28%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	64/231 (28%)