Protein Alignment CG4477 and KLK3

DIOPT Version :10

• Sequence 1: NP_648295.1
• Gene: CG4477 / 39058
• FlyBaseID: FBgn0035971
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 63/230 - (27%)
• Similarity: 98/230 - (42%)
• Gaps: 40/230 - (17%)

  Fly    72 CSGVILAPMFVMTSAHCLINKRRVLISSRVLLIVAGTLNRLKYIPNRT-FVTPVTHIW---LPDS 132
            |.||::.|.:|:|:|||:.||..:|:....|           :.|..| .|..|:|.:   |.|.
Human    50 CGGVLVHPQWVLTAAHCIRNKSVILLGRHSL-----------FHPEDTGQVFQVSHSFPHPLYDM 103

  Fly   133 FTMRNK---------QDFGLLKVKNPFPRNNEHISIARLPVHPPLPGLKCKVMGWGRMYKGGPLA 188
            ..::|:         .|..||::..| ....:.:.:..||...|..|..|...|||.:.....|.
Human   104 SLLKNRFLRPGDDSSHDLMLLRLSEP-AELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLT 167

  Fly   189 SYMLY-IDVQVIDSEACAKWLRVPSVEHVCAVDSDDLTA------QQPCGGDWGAPMLHNGTVYG 246
            ...|. :|:.||.::.||:       .|...|....|.|      :..|.||.|.|::.||.:.|
Human   168 PKKLQCVDLHVISNDVCAQ-------VHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQG 225

  Fly   247 IVTI-LAGCGVSHLPSLYTNVHSNANWIHEKIISS 280
            |.:. ...|.:...|||||.|.....||.:.|:::
Human   226 ITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4477	NP_648295.1	Tryp_SPc	55..276	CDD:238113	62/224 (28%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	62/224 (28%)