Protein Alignment CG4483 and ZDHHC12

DIOPT Version :9

• Sequence 1: NP_648294.1
• Gene: CG4483 / 39057
• FlyBaseID: FBgn0035970
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_001304944.2
• Gene: ZDHHC12 / 84885
• HGNCID: 19159
• Length: 322
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 74/287 - (25%)
• Similarity: 114/287 - (39%)
• Gaps: 74/287 - (25%)

  Fly     1 MCIKLKDDLRRFIHWGPITL-LTLTLIVTWTVIHMNSMWWAPGSSLESVLNYALIWIQTFGTLYN 64
            :|.....:||::...|.:.| ||..|:|                               .|:|..
Human    82 LCSPASPELRQWEEQGELLLPLTFLLLV-------------------------------LGSLLL 115

  Fly    65 FIRSLMVGPGFVPLKWHPQ---------LTKDKMFLQFCTRCNGYKAPRSHHCRRCNRCVMKMDH 120
            ::...::.||:|.::..||         :....:.|:.|..|...:..|:.|||.|.|||.:.||
Human   116 YLAVSLMDPGYVNVQPQPQEELKEEQTAMVPPAIPLRRCRYCLVLQPLRARHCRECRRCVRRYDH 180

  Fly   121 HCPWINTCVGWSNQDSFVYFLLFFMSGSIHGGIIIVSAVIRGIK-----KRWLIRYGLRHMATVH 180
            ||||:..|||..|...||.:|...:...:.|..:..|    |::     .:||...||
Human   181 HCPWMENCVGERNHPLFVVYLALQLVVLLWGLYLAWS----GLRFFQPWGQWLRSSGL------- 234

  Fly   181 LTQTNLLACVFSLGVIMGTVLASIKLLYMQMKSILKNQTEIENWIVKKAAFRRNAYPRKGIKPFV 245
            |..|.||..:|||       :||: ||...:..:..|.|   .|  :..:..|.||.|:  :| .
Human   235 LFATFLLLSLFSL-------VASL-LLVSHLYLVASNTT---TW--EFISSHRIAYLRQ--RP-S 283

  Fly   246 YPYNLGWKTNMREVFFSTGDGISWPVL 272
            .|::.|...|:...|.....| ||..|
Human   284 NPFDRGLTRNLAHFFCGWPSG-SWETL 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4483	NP_648294.1	zf-DHHC	88..224	CDD:279823	44/140 (31%)
ZDHHC12	NP_001304944.2	DHHC	<178..272	CDD:388695	34/117 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900