DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4483 and zdhhc15b

DIOPT Version :9

Sequence 1:	NP_648294.1	Gene:	CG4483 / 39057	FlyBaseID:	FBgn0035970	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001071249.1	Gene:	zdhhc15b / 777734	ZFINID:	ZDB-GENE-061110-106	Length:	332	Species:	Danio rerio

Alignment Length:	331	Identity:	80/331 - (24%)
Similarity:	126/331 - (38%)	Gaps:	119/331 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RRFIHWGPITLLTLTLIVTWTVIHMNSMWWAPGSSLESVLNYALIWIQTFGTLYN---------- 64
            :|...|.|:  :.::.:|.|:.                   ||.::...|.||.|
Zfish    11 QRIFSWIPV--IIISSVVLWSY-------------------YAYVFELCFVTLSNNLGRVTYLLI 54

  Fly    65 ----FI-------RSLMVGPGFVPLKWH--------------PQLTKDKMF-------------- 90
                ||       :::...|.....|:|              |::.|..:.
Zfish    55 FHVCFIMFCWTYWKAIFTPPSTPTKKFHLSYTDKERYEMEERPEVQKQILVDIAKKLPIFTRAQS 119

  Fly    91 --LQFCTRCNGYKAPRSHHCRRCNRCVMKMDHHCPWINTCVGWSNQDSFVYFLLFFMSGSIHGGI 153
              ::||.||...|..|.|||..|..||:||||||||:|.|||:||   :.:||| |:|.|:...:
Zfish   120 GAIRFCDRCQVIKPDRCHHCSVCETCVLKMDHHCPWVNNCVGFSN---YKFFLL-FLSYSMIYCV 180

  Fly   154 IIVSAVIRGIKKRWL--IRYGLRHMATVHLTQTNLLACVFSLGVIMGTVLASIKLLYMQMKSILK 216
            .|.|.|.:...|.|:  :..|   .|..|:.....:|.:|.:.::.        |.......:.|
Zfish   181 FIASTVFQYFLKFWVGDLPNG---PAKFHVLFLLFVALMFFVSLMF--------LFGYHCWLVAK 234

  Fly   217 NQTEIENWIVKKAAFR----RNAYPRKGIKPFVYPYNLGWKTNMRE------------VFFSTGD 265
            |::.:|       ||.    :|...|.|       :|:|...|:|:            ||.|.||
Zfish   235 NRSTLE-------AFSPPVFQNGPDRNG-------FNVGLNKNLRQVFGEHKKLWFIPVFTSQGD 285

  Fly   266 GISWPV 271
            |..:|:
Zfish   286 GHYFPL 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4483	NP_648294.1	zf-DHHC	88..224	CDD:279823	46/153 (30%)
zdhhc15b	NP_001071249.1	zf-DHHC	16..292	CDD:303066	79/326 (24%)
zdhhc15b	NP_001071249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..332
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820