DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4483 and zdhhc3b

DIOPT Version :9

Sequence 1:	NP_648294.1	Gene:	CG4483 / 39057	FlyBaseID:	FBgn0035970	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001071225.1	Gene:	zdhhc3b / 777709	ZFINID:	ZDB-GENE-061110-19	Length:	300	Species:	Danio rerio

Alignment Length:	266	Identity:	77/266 - (28%)
Similarity:	117/266 - (43%)	Gaps:	52/266 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 IVTWTVIHMNS------MWWAPGSSLESVLNYALIWIQTFGTLYNFIRSLMVGPGFVPLKWHPQL 84
            ::||.::....      |.....|.|.|.:|.||.....|..|.:.:|::...||.||   ....
Zfish    50 VITWLLVLYAEFVVVFVMLLPARSLLYSFINGALFNSLAFLALASHLRAMCTDPGAVP---KGNA 111

  Fly    85 TKDKMFLQF-----------CTRCNGYKAPRSHHCRRCNRCVMKMDHHCPWINTCVGWSNQDSFV 138
            ||:  |::.           |.:|...|..|:|||..|.||:.||||||||:|.|||.:||..||
Zfish   112 TKE--FIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIKKMDHHCPWVNNCVGENNQKYFV 174

  Fly   139 YFLLFFMSGSIHGGIIIVSAVIRGIKKRWLIRYGLRHMATVHLTQTNLLACVFSL------GVIM 197
            .|.::....|:|..:::....:...::.|.........|||.|.   :|.|..:|      .|:.
Zfish   175 LFTMYIALISLHALLMVAFHFVFCFEEDWAKCSSFSPPATVILL---ILLCFEALLFLIFTAVMF 236

  Fly   198 GTVLASIKLLYMQMKSILKNQTEIENWIVKKAAFRRNAYPRKGIK---PFVYPYNLGWKTNMREV 259
            ||          |:.||..::|.||.  :||.. ||.|...|.:.   .|.:|:::.|.:.
Zfish   237 GT----------QVHSICNDETGIEQ--LKKEE-RRWAKRSKWMNMKVVFGHPFSMSWMSP---- 284

  Fly   260 FFSTGD 265
             |:|.|
Zfish   285 -FATPD 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4483	NP_648294.1	zf-DHHC	88..224	CDD:279823	47/152 (31%)
zdhhc3b	NP_001071225.1	zf-DHHC	130..256	CDD:279823	47/140 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820