DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4483 and Zdhhc21

DIOPT Version :9

Sequence 1:	NP_648294.1	Gene:	CG4483 / 39057	FlyBaseID:	FBgn0035970	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_080923.2	Gene:	Zdhhc21 / 68268	MGIID:	1915518	Length:	265	Species:	Mus musculus

Alignment Length:	232	Identity:	65/232 - (28%)
Similarity:	92/232 - (39%)	Gaps:	69/232 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LYNFIRSLMVGPGFVPLKWHPQLT-KDKMFLQFCTRCNGYKAPRSHHCRRCNRCVMKMDHHCPWI 125
            |...:|:.:..||.:|  .:|::. .::...:.|.:||..:..|||||.||..||.:||||||||
Mouse    61 LVALVRASLTDPGRLP--ENPKIPHAERELWELCNKCNLMRPKRSHHCSRCGHCVRRMDHHCPWI 123

  Fly   126 NTCVGWSNQDSFV-----------YFLLF-------FMSGSIHGGIIIVSAVIRGIKKRWLIRYG 172
            |.|||..|...|:           |.|:|       |:.                :|||.|..:.
Mouse   124 NNCVGEDNHWLFLQLCFYTELLTCYALMFSFCHYYYFLP----------------LKKRNLDLFV 172

  Fly   173 LRHMATVHLTQTNLLACVFSLGVIMG-TVLASIK-LLYMQMKSILKNQTEIENWIVKKAAFRRNA 235
            :||.           ..:..|...|| |:|..|. |.|.|:..|:.:.|.||.   ........:
Mouse   173 VRHE-----------LAIMRLAAFMGITMLVGITGLFYTQLIGIITDTTSIEK---MSNCCEEIS 223

  Fly   236 YPRKGIKPFVYPYNLGWKTNMREVFFSTGDGISWPVL 272
            .|||           .|:....|||     |..|.:|
Mouse   224 RPRK-----------PWQQTFSEVF-----GTRWKIL 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4483	NP_648294.1	zf-DHHC	88..224	CDD:279823	49/155 (32%)
Zdhhc21	NP_080923.2	DHHC	92..217	CDD:396215	49/154 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810