Protein Alignment CG4483 and ZDHHC4

DIOPT Version :10

• Sequence 1: NP_648294.1
• Gene: CG4483 / 39057
• FlyBaseID: FBgn0035970
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_001358221.1
• Gene: ZDHHC4 / 55146
• HGNCID: 18471
• Length: 359
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 85/339 - (25%)
• Similarity: 138/339 - (40%)
• Gaps: 90/339 - (26%)

  Fly     2 CIKLKDDLRRFIHWGPITLLTLTLIVTWTVIHM--------NSMWWAPG--SSLESVLNYALIWI 56
            || :.:.|:|.:| |.:..|..|...|:.|:|:        ...|...|  ..||..|:|.|:..
Human    43 CI-IPECLQRAVH-GLLHYLFHTRNHTFIVLHLVLQGMVYTEYTWEVFGYCQELELSLHYLLLPY 105

  Fly    57 QTFG-TLYNFIRSLMVGPGFVPLKWHPQLTK--DKMFLQF-------------CTRCNGYKAPRS 105
            ...| .|:.|..:....||.:        ||  :.:||..             |:.|:..|..||
Human   106 LLLGVNLFFFTLTCGTNPGII--------TKANELLFLHVYEFDEVMFPKNVRCSTCDLRKPARS 162

  Fly   106 HHCRR---------------CNRCVMKMDHHCPWINTCVG-WSNQDSFVYFLLFFMSGSIHGGII 154
            .||..               ||.||.:.||||.|:|.|:| |:.:    |||::.::.:.....:
Human   163 KHCSECGSRDSSGTSNSTCVCNWCVHRFDHHCVWVNNCIGAWNIR----YFLIYVLTLTASAATV 223

  Fly   155 -------IVSAVIRG--IKKRWLIRYGLRH-MATVHLTQTNLLA---CVFSLG--VIMGTVLASI 204
                   :|..|:..  .::.::...|..| |.||.|.|...|.   .||.||  |::..:|...
Human   224 AIVSTTFLVHLVVMSDLYQETYIDDLGHLHVMDTVFLIQYLFLTFPRIVFMLGFVVVLSFLLGGY 288

  Fly   205 KLLYMQMKSILKNQTEIENWIVKKAAFRRN----AYPRKGIKPFVYP--YNLGWKTNMREVFFST 263
            .|..:.:.:  .|||..| |.....|:.:.    |:| ...:|.|:.  ::.|.::|::|:|.
Human   289 LLFVLYLAA--TNQTTNE-WYRGDWAWCQRCPLVAWP-PSAEPQVHRNIHSHGLRSNLQEIFL-- 347

  Fly   264 GDGISWPVLPDCNE 277
                  |..| |:|
Human   348 ------PAFP-CHE 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4483	NP_648294.1	DHHC	88..224	CDD:396215	46/179 (26%)
ZDHHC4	NP_001358221.1	DHHC	151..307	CDD:396215	45/162 (28%)