DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4483 and Dnz1

DIOPT Version :9

Sequence 1:	NP_648294.1	Gene:	CG4483 / 39057	FlyBaseID:	FBgn0035970	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster

Alignment Length:	253	Identity:	66/253 - (26%)
Similarity:	106/253 - (41%)	Gaps:	87/253 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LIVTWTVIHMNSMWWAPGSSLESVLNYALIWIQTFGTLYNFI---------RSLMVGPGFVPL-- 78
            :::.|.:  :.:|   |||          :|:.....|:|.:         :::...||.|||
  Fly    26 VVIRWII--LTTM---PGS----------LWMSFHVVLFNTVVFLLAMSHSKAVFSDPGTVPLPA 75

  Fly    79 ------------------------KWHPQLTKDKMFLQFCTRCNGYKAPRSHHCRRCNRCVMKMD 119
                                    :|           ..||||..|:.||:||||.|.||:.:||
  Fly    76 NRLDFSDLHTTNKNNPPPGNGHSSEW-----------TVCTRCETYRPPRAHHCRICKRCIRRMD 129

  Fly   120 HHCPWINTCVGWSNQDSFVYFLLFFMSGSIHGGIIIVSAVIRGIKKRW--------LIRYGLRHM 176
            |||||||.|||..||..|:.||::....|::...:||.:.:      |        :|...||
  Fly   130 HHCPWINNCVGERNQKYFLQFLIYVALLSLYSIALIVGSWV------WPCEECSQNVIETQLR-- 186

  Fly   177 ATVHLTQTNLLACVFSLGVIMGTVLASIKLLYMQMKSILKNQTEIENWIVKKAAFRRN 234
             .:|.....|::.:|.|.|        ..::..|:.:||.::|.:|. |.:|..:|.|
  Fly   187 -MIHSVILMLVSALFGLFV--------TAIMVDQLHAILYDETAVEA-IQQKGTYRPN 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4483	NP_648294.1	zf-DHHC	88..224	CDD:279823	48/143 (34%)
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	50/159 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467527
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22883
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850