DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4483 and Zdhhc5

DIOPT Version :9

Sequence 1:	NP_648294.1	Gene:	CG4483 / 39057	FlyBaseID:	FBgn0035970	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_659136.1	Gene:	Zdhhc5 / 228136	MGIID:	1923573	Length:	715	Species:	Mus musculus

Alignment Length:	267	Identity:	65/267 - (24%)
Similarity:	103/267 - (38%)	Gaps:	55/267 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PITLLTLTLIVTWTVIHMNSMWWAPGSSLE---SVLNYALIWIQTFGTLYNFIRSLMVGPGFVPL 78
            |::...:.|:...|:..   .:..||.||.   :|..|..|..  ...|.||..:..:.||..|.
Mouse    16 PVSAAAIFLVGATTLFF---AFTCPGLSLNVSPAVPIYNAIMF--LFVLANFSMATFMDPGIFPR 75

  Fly    79 KWHPQLTKD---------------KMFLQFCTRCNGYKAPRSHHCRRCNRCVMKMDHHCPWINTC 128
            ....:..:|               ::.:::|..|..|:.||..||..|:.||.:.||||||:|.|
Mouse    76 AEEDEDKEDDFRAPLYKTVEIKGIQVRMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNC 140

  Fly   129 VGWSNQDSFVYFLLFFMSGSIHGGIIIVSAVIRGIKKRWL--IRYGLRHMATVHLTQTNLLACVF 191
            :|..|   :.||.||.:|.:.|         |.|:....|  :.|.:..::.|....|..:.||.
Mouse   141 IGRRN---YRYFFLFLLSLTAH---------IMGVFGFGLLYVLYHIEELSGVRTAVTMAVMCVA 193

  Fly   192 SLGVIMGTVLASIKLLYMQMKSILKNQTEIENWIVKKAAFRRNAYPRKGIKPFVYPYNLGWKTNM 256
            .|..|....|....::.     :.:.:|..|....|.         |.|:.||..    |...|:
Mouse   194 GLFFIPVAGLTGFHVVL-----VARGRTTNEQVTGKF---------RGGVNPFTN----GCCNNV 240

  Fly   257 REVFFST 263
            ..|..|:
Mouse   241 SRVLCSS 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4483	NP_648294.1	zf-DHHC	88..224	CDD:279823	39/137 (28%)
Zdhhc5	NP_659136.1	zf-DHHC	99..224	CDD:279823	39/141 (28%)
Zdhhc5	NP_659136.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..715
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810