DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4483 and dhhc-13

DIOPT Version :9

Sequence 1:	NP_648294.1	Gene:	CG4483 / 39057	FlyBaseID:	FBgn0035970	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_500889.2	Gene:	dhhc-13 / 186797	WormBaseID:	WBGene00019257	Length:	593	Species:	Caenorhabditis elegans

Alignment Length:	297	Identity:	74/297 - (24%)
Similarity:	113/297 - (38%)	Gaps:	99/297 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 FIHWGPITLLTLTL-----IVTWTV-IHMNSMWWAPGSSLESVLNYALIWIQTFGTLYNFIRSLM 70
            :|.|..|....|.:     :|.|:| |.:.|:|         |::.:..||           .::
Worm   335 YIFWMGIAEFALLIFNSNGLVHWSVLIFVCSIW---------VISASFYWI-----------LIL 379

  Fly    71 VGPGFVPLKWHP--QLTKD---KMFLQFCTRCNGYKAPRSHHCRRCNRCVMKMDHHCPWINTCVG 130
            ..||.:|....|  ...||   |...::|..|...|...||||.:|::||...|||||||:.||.
Worm   380 TNPGVLPRSTTPFKDFIKDLEEKQIDRYCFTCWIPKTSSSHHCSQCDKCVDGFDHHCPWIHKCVY 444

  Fly   131 WSNQDSFVYF--------------LLFFMSGSIHG----------GIIIVSAVIRGIKKRWLIRY 171
            ..|..:||:|              ||:.:..|::.          |::::|.:
Worm   445 RKNLRAFVFFCLTIFMFHVFYVLLLLYMIGASMNASGFEQTLNDHGLMVISLI------------ 497

  Fly   172 GLRHMATVHLTQTNLLACVFSLGVIMGTVLASIKLLYMQMKSILKNQTEIENWIVKKAAFRRNAY 236
                :|..|         ||..|.|..|          |...|.::.:.||  |::|...:||:.
Worm   498 ----LAIPH---------VFGAGAITCT----------QFSQISRHVSTIE--IIRKQRLQRNSS 537

  Fly   237 PRKGIKPFVYP--YNLGWKTNMREV-----FFSTGDG 266
            .:....|...|  |....||.:|.|     |...|||
Worm   538 EKTITSPEHNPWEYKQSVKTRIRNVCNLLAFDKFGDG 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4483	NP_648294.1	zf-DHHC	88..224	CDD:279823	40/159 (25%)
dhhc-13	NP_500889.2	ANK	42..155	CDD:238125
		Ank_2	42..132	CDD:289560
		ANK repeat	67..98	CDD:293786
		ANK repeat	101..132	CDD:293786
		Ank_5	121..176	CDD:290568
		ANK	130..>240	CDD:238125
		Ank_5	198..243	CDD:290568
		ANK repeat	206..234	CDD:293786
		zf-DHHC	405..530	CDD:279823	40/161 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810