DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4483 and dhhc-14

DIOPT Version :9

Sequence 1:	NP_648294.1	Gene:	CG4483 / 39057	FlyBaseID:	FBgn0035970	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001024514.2	Gene:	dhhc-14 / 181109	WormBaseID:	WBGene00044071	Length:	565	Species:	Caenorhabditis elegans

Alignment Length:	288	Identity:	64/288 - (22%)
Similarity:	107/288 - (37%)	Gaps:	70/288 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DDLRRFIHWGPITLLTLTLIVTWTV-IHMNSMWWAPGSSLESVLNYALIWIQTFGTLYNFIRSLM 70
            |...:.:.:|......:.::::|:. .|....|||....:.|||..|....: .|||
Worm   316 DPTYKLLPYGVTIAEAILMVLSWSAYAHWYVPWWAQMLFVLSVLALAFTLFR-IGTL-------- 371

  Fly    71 VGPGFVPLKWHPQLTKD--KMFL-----------QFCTRCNGYKAPRSHHCRRCNRCVMKMDHHC 122
             .||.|      :..|:  ::|:           ::|..|...|...:.||..|..||...||||
Worm   372 -DPGVV------RAAKNCHQLFVNEAEAGIQHQQKYCFTCFIRKMDHTKHCAVCGFCVNNFDHHC 429

  Fly   123 PWINTCVGWSNQDSFVYFLLFFMSGSIHGGIIIVSAVIRGIKKRWLIRYGLRHMATVHLTQTNLL 187
            ||:|:||...|...|:   :|.:|.|:...|..::.               .|.|.:.:....|.
Worm   430 PWLNSCVTRRNMREFI---MFVISVSVSSAIYCMAT---------------SHYALLQIEDHGLE 476

  Fly   188 ACVFSLGVIMGTVLASIK-------LLYMQMKSILKNQTEIENWIVKKAAFRRNAYPRKGIKPFV 245
            ..:.:...:|.|::.|..       |..:||..|.:..|..:....::|.   :|:...|..
Worm   477 EFLETDAFLMITIILSAMHALMLAVLFCVQMNQISQGVTTNDRIKARRAG---HAHSHSGST--- 535

  Fly   246 YPYNLGWKT--------NMREVFFSTGD 265
             .||:....        |:.|.|.|.||
Worm   536 -DYNVIHHKPSISKRCHNLLEFFSSNGD 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4483	NP_648294.1	zf-DHHC	88..224	CDD:279823	35/153 (23%)
dhhc-14	NP_001024514.2	ANK	19..143	CDD:238125
		Ank_2	30..120	CDD:289560
		ANK repeat	55..87	CDD:293786
		ANK repeat	89..120	CDD:293786
		Ank_2	94..222	CDD:289560
		ANK	117..244	CDD:238125
		ANK repeat	190..222	CDD:293786
		PulO	<261..>367	CDD:224900	11/50 (22%)
		zf-DHHC	394..521	CDD:279823	34/144 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910