Protein Alignment CG4476 and SLC6A13

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_057699.2
• Gene: SLC6A13 / 6540
• HGNCID: 11046
• Length: 602
• Species: Homo sapiens
• Alignment Length: 599
• Identity: 217/599 - (36%)
• Similarity: 331/599 - (55%)
• Gaps: 41/599 - (6%)

  Fly    20 SRCAG---SGEALLKPSLLPMALESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTA 81
            ||.:|   :||.  || :.|: :|..| ......|.:|.:.:||::|.....:|||||||||:..
Human     3 SRVSGTTSNGET--KP-VYPV-MEKKE-EDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLC 62

  Fly    82 LENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFSSRGIVQVF-DFAPLMRGVGYAQLLALGVLAT 145
            .:||||||.|||||.||..|.|::.:|..|||::|:|.|..: ...|:..|:|||..:.:.:|..
Human    63 YKNGGGAFFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNV 127

  Fly   146 YYASVMALTLRYFFDSFASELPWSFCREEWG-DGCVSASGGQPLQGQL---SRNFSSSTQLYLQR 206
            ||..|:|..|.|.|.||..:|||..|..||. :.|:..   |...|.|   |.|.:|....:.:|
Human   128 YYIIVLAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEF---QKTNGSLNGTSENATSPVIEFWER 189

  Fly   207 IVLNETDSLEEGIGYPSGSLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRAL 271
            .||..:|.::. :|.....|||.|.::|:.....|.:||||:||..|..|.|||:::.:||:|.:
Human   190 RVLKISDGIQH-LGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGV 253

  Fly   272 TLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVT 336
            |||||..|:.::|.|...:|.:||||.:|.||:|||.|:|.|.:....|||::.:|.|||...:.
Human   254 TLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALC 318

  Fly   337 TLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVFSLLFFA 401
            .|::.||.::|..||.|||.::.|.|. .|:.|.::|||||||:||.|:......| :::..||.
Human   319 FLNSGTSFVAGFAIFSILGFMSQEQGV-PISEVAESGPGLAFIAYPRAVVMLPFSP-LWACCFFF 381

  Fly   402 MLFMLGVGSNVGMVSCIMTVLKDQFVNV-----KLWIIVVSLSVIGFLVGLIYITPGGQHIITLM 461
            |:.:||:.|....|..::|.|.|.:.:|     :..::::.:||:.||||||.:|.||.::..|.
Human   382 MVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQLF 446

  Fly   462 DFHGVTFVSLV-SAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYS 525
            |::..:.:.|: .||||.:.|.|:||.||...:.|.|:..:.....:.||..:||.|.....::|
Human   447 DYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCTATFLFS 511

  Fly   526 LLTMRPLSYNGQ-EFPLVYRVVGWCVS----GCIIGQLFYWAGYANFKQPKGSLKSRINNSIKPH 585
            |:...||:||.: .:|.....:||.::    .||.....|..|..     ||..:.||...:.|.
Human   512 LIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGTL-----KGPFRERIRQLMCPA 571

  Fly   586 SDW------GPSDP 593
            .|.      |||.|
Human   572 EDLPQRNPAGPSAP 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	183/484 (38%)
SLC6A13	NP_057699.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		8/22 (36%)
		SLC6sbd_GAT2	32..575	CDD:271396	203/553 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820