Protein Alignment CG4476 and slc6a15

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001232001.1
• Gene: slc6a15 / 565315
• ZFINID: ZDB-GENE-050420-93
• Length: 741
• Species: Danio rerio
• Alignment Length: 644
• Identity: 205/644 - (31%)
• Similarity: 322/644 - (50%)
• Gaps: 125/644 - (19%)

  Fly     1 MKDL-----------KTEILVSGGLPKLETSRC-AGSGEALLKPSLLPMALESSELSPDRKARDN 53
            :|||           |...|:.|.:|:.:.... .||.|            |..|...:|.|
Zfish    21 VKDLLSNEDSCDDSFKKSSLMVGDVPQNKQKDVEEGSEE------------EEEEEEEERPA--- 70

  Fly    54 WGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFSSRG 118
            |||.|:::::.:..|||||||||||:...:|||||:|:|||::|.::|.|::::|:.:||...||
Zfish    71 WGSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYLILLLLIGIPLFFLELAVGQRIRRG 135

  Fly   119 IVQVFDF-APLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASELPWSFCREEWGDGCVSA 182
            .:.|::: :|.:.|:|:|..|....:|.||..::..:|.||..||...|||..|
Zfish   136 SIGVWNYISPHLGGIGFASCLVCFFVALYYNVIIGWSLFYFSQSFQQPLPWHEC----------- 189

  Fly   183 SGGQPLQGQLSRNF-------SSSTQLYLQRIVLNETDSLEEGIGYPSGSLALMLGISWLTVTLI 240
                ||....:..:       ||:|..|..|:.|:.:||:.||.|. :..:.|.|..:|..|.|.
Zfish   190 ----PLVKNKTNTYIEPECEKSSATTYYWYRVALDISDSISEGGGL-NWRMTLCLLAAWTMVCLA 249

  Fly   241 IIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVF 305
            :|:|::||||..|..:||||||:...|.||..|.|:.||:::..||:.|.:|||:||..|.||||
Zfish   250 MIKGIQSSGKVMYFSSLFPYVVLICFLARAFLLKGSVDGIIHMFTPKLEIMLEPKVWREAATQVF 314

  Fly   306 FSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGILGNLAH-------ESGT 363
            |:|.:.||.:|.:||||:..:|.:.||.:|:.::.|||:|:.:::|.:||..|:       |..|
Zfish   315 FALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIMNAKCVEMNT 379

  Fly   364 KDIASVV-----------------------------------------------------KA--G 373
            |.|...:                                                     ||  |
Zfish   380 KKIIGFLGKEINPGLIPHHINFSQVSPEDYQQMTNIIQGVMENDYPRLGLDNCDIKEELNKAVQG 444

  Fly   374 PGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVNVKLWIIVVSL 438
            .|||||::.:|:..|...| .:|::||.||..||:||..|.:..|:|.:.|.| .|:...:.|..
Zfish   445 TGLAFIAFTEAMTHFPASP-FWSVMFFLMLVNLGLGSMFGTIQGILTPIVDTF-KVRKEYLTVGC 507

  Fly   439 SVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKRLCQDAEYMLNIKTS 503
            .|:.|.:||.::...|.:.:.:.|.:..|...|:..:.|.|||.|:|||.:..:|.:.||.....
Zfish   508 CVLAFFIGLTFVQRSGNYFVAMFDDYSATLPLLIVVLLENIAVAWVYGTDKFFEDLKDMLGFTPY 572

  Fly   504 NYYRICWSIVTPLVMLVILVYSL--LTMRPLSYN------GQEFPLVYRVVGWCVSGCI 554
            .||...|..|||:::|.:|..|:  |.:.|.||:      .:|..|.|  ..|.::.||
Zfish   573 RYYYYMWKFVTPVLLLGLLAASVIQLGLAPPSYSAWNQQLAKEQSLSY--PPWGLAVCI 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	180/543 (33%)
slc6a15	NP_001232001.1	SLC5-6-like_sbd	68..646	CDD:294310	193/585 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010