Protein Alignment CG4476 and slc6a7

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_005161359.1
• Gene: slc6a7 / 562050
• ZFINID: ZDB-GENE-070112-1492
• Length: 652
• Species: Danio rerio
• Alignment Length: 617
• Identity: 220/617 - (35%)
• Similarity: 335/617 - (54%)
• Gaps: 68/617 - (11%)

  Fly    14 LPKLETSRCAGSGEALLKPSL-----------LPMALESSELS-----PDRKARDNWGSSLEFLM 62
            :|..|.....|:| .:..||.           .|:|.:|...|     |.:..||.||...|||:
Zfish    19 MPTEEARTAPGNG-VITTPSTENPAHQNGAVSSPVASQSQPPSSAASPPAQPPRDQWGGKYEFLL 82

  Fly    63 SCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFSSRGIVQVFDFAP 127
            |||...||||||||||:....||||.|||||.::||..|.|::.||:.|||:.:.|.:.|:...|
Zfish    83 SCIGYCVGLGNVWRFPYLCYRNGGGVFLIPYFIMLFFTGMPLFLMELSLGQYGAAGPITVWKCCP 147

  Fly   128 LMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASELPWSFCREEWGDGCVSASGGQPLQG-Q 191
            |::|:|...|....::..||..::|.|..|...||.|.||||         |      ..||. .
Zfish   148 LLKGIGIGMLCVSTLVCLYYNVIIAWTFYYLGSSFQSPLPWS---------C------DALQNIA 197

  Fly   192 LSRNFSSSTQ-----LYLQRI--VLNETDSLEEG-IGYPSGSLALMLGISWLTVTLIIIRGVKSS 248
            |..|.::|||     .:.:::  |::.|...:.| :.:|   |||.|..:|:.:.|.:::|:.||
Zfish   198 LCANKTNSTQSPSEVFWNEKVLGVVHSTGLSDPGPVRWP---LALCLLAAWIIIFLCMLKGIHSS 259

  Fly   249 GKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFG 313
            ||..||.|.|||.|:.:|::|..||.|:.|||.::|||:|::|.:.|||.:|.:|:|:||.:..|
Zfish   260 GKVVYVTATFPYFVLLVLIIRGATLEGSLDGVAFYLTPKWDQLADAQVWNDAASQIFYSLGIGVG 324

  Fly   314 VIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAF 378
            .::..:|||:|.:||.||..|:|..:..||..:|..||.|||::|.:.|. .:..|..:||||||
Zfish   325 GLLSMASYNKFDNNVIRDTIIITIGNCSTSFFAGFAIFSILGHMAFKKGV-PVDKVADSGPGLAF 388

  Fly   379 ISYPDAIAKFKMFP-QVF-SLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVNVK-------LWII 434
            ::||:|:|   :.| .|| |:|||.|||||||.:..|.:..|.|.:.|:|..::       |::.
Zfish   389 VAYPEALA---LLPGSVFWSILFFLMLFMLGVDTLFGNMEGICTAVLDEFPQLRSNLKHKTLFLA 450

  Fly   435 VVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKRLCQDAEYML- 498
            |:..|.  :|:||:.||.||.:..||:|....:|..::..:|..|.:.:.||..:.|||...|:
Zfish   451 VLCFSF--YLMGLLLITDGGIYWFTLIDSFSTSFGLIIITLFMCIGISFFYGVNQFCQDIVDMIC 513

  Fly   499 -----NIKTSNYYRICWSIVTPLVMLVILVYSLLTM--RPLSYNGQEFPLVYRVVGWCVSGCIIG 556
                 ..|...|::.||.:.||.::..||.|..:.|  ..|.|....:|:..:.:|.|:......
Zfish   514 RCPPWCTKMLLYFKACWVVFTPFLLTFILTYIFIEMYRTSLRYGSYVYPIWGKALGVCMGALCCL 578

  Fly   557 QLFYWAGYANFKQPKGSLKSRINNSIKPHSDW 588
            |:..||..|..|: .|:||.|...||:|.:.|
Zfish   579 QILIWAIVAISKE-SGTLKDRFKKSIRPLNSW 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	189/497 (38%)
slc6a7	XP_005161359.1	SLC5-6-like_sbd	71..610	CDD:294310	209/564 (37%)
		PotE	<235..564	CDD:223605	126/337 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920