Protein Alignment CG4476 and slc6a11a

DIOPT Version :10

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001091857.1
• Gene: slc6a11a / 558960
• ZFINID: ZDB-GENE-030131-3729
• Length: 590
• Species: Danio rerio
• Alignment Length: 600
• Identity: 207/600 - (34%)
• Similarity: 325/600 - (54%)
• Gaps: 46/600 - (7%)

  Fly    40 ESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKPI 104
            :.::::|:.  |..|.:.:|||::.....:|||||||||:...:||||||.|||::.|...|.|:
Zfish    12 QQADITPEE--RGQWANKIEFLLTVAGAIIGLGNVWRFPYLCYKNGGGAFFIPYVLYLVTCGIPL 74

  Fly   105 YYMEMLLGQFSSRGIVQVF-DFAPLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASELPW 168
            :.:|..|||::|:|.:..: ...||..|:|||..|.:...:..|..::|....|.|.||..||||
Zfish    75 FVLETSLGQYTSQGGIMCWRKVCPLFEGMGYASQLIIVYGSITYIIIIAWAFLYLFSSFNVELPW 139

  Fly   169 SFCREEWG-DGCVSASG-------GQPLQGQLSRNFSSSTQLYLQRIVLNETDSLEEGIGYPSGS 225
            :.|...|. |.|:..||       ..||      |.|||...:....||..:..:|. :|.....
Zfish   140 ASCNNPWNTDTCIVLSGRNSSSELASPL------NSSSSVMEFWHHRVLRLSSGVEH-LGTVRWD 197

  Fly   226 LALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWEK 290
            |||:|.:.|:.|...|.:||||:|||.|..|.||||::.|||:|.:|||||.:|:.|::.|...:
Zfish   198 LALILLLVWILVYFCIWKGVKSTGKAVYFTATFPYVMLLILLLRGVTLPGALNGIYYYMYPDLTR 262

  Fly   291 LLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGILG 355
            |.:||||.:|.||:|:|.|:|.|.:....|||::.:|.|||:..:..|::.||.|.|..||.:||
Zfish   263 LADPQVWMDAGTQIFYSYAICLGYLSSLGSYNQYNNNCYRDSFYLCLLNSGTSFLGGFAIFSVLG 327

  Fly   356 NLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFP--QVFSLLFFAMLFMLGVGSN-VGMVSC 417
            ::|.|.|. ||:.|.::||||.||.||.|:.   |.|  |.:::.||.|:.:||:.|. ||:.|
Zfish   328 HMAQEQGV-DISLVAESGPGLVFIVYPQAVT---MLPLSQFWAVCFFIMIILLGLDSQFVGLES- 387

  Fly   418 IMTVLKDQFVNV-----KLWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFH---GVTFVSLVSA 474
            |||.:.|.|..|     :..::::.:.::.:.:||:.||.||.:||.|.|.:   |.|.:.|  |
Zfish   388 IMTSVTDIFPTVLRRGFRREMLLLGICLVCYFMGLLMITEGGLYIIQLFDHYVCSGTTLLFL--A 450

  Fly   475 IFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYSLLTMRPLSYNGQ-E 538
            ..:.:|:||:||..|..::.:.|:..|.....:.||..|||.|.:...::||:...||.:|.: .
Zfish   451 TCQSVAIGWVYGADRFYENIQDMIGYKPWPMVKYCWLYVTPSVCVGTFIFSLVKYSPLKFNNKYM 515

  Fly   539 FPLVYRVVGWCVS----GCIIGQLFYWAGYANFKQPKGSLKSRINNSIKPHSDWGPSDPKKLMDY 599
            :|.....:||.::    ..|...:.|     ...:.||:...|:..:..|..|...|.......|
Zfish   516 YPWWAYGIGWFLAVSSLSLIPINMIY-----KLHKGKGTFWERLQLACSPAEDLPQSQRPSAHHY 575

  Fly   600 QMFLRNKDEENSKNV 614
            .:......|::..|:
Zfish   576 TLSASTDREKSPDNL 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	186/493 (38%)
slc6a11a	NP_001091857.1	SLC6sbd-TauT-like	21..560	CDD:271387	200/557 (36%)