Protein Alignment CG4476 and SerT

DIOPT Version :10

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Alignment Length: 583
• Identity: 209/583 - (35%)
• Similarity: 318/583 - (54%)
• Gaps: 45/583 - (7%)

  Fly    36 PMA--LESSE----LSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYL 94
            |:|  |.::|    :|...:.|:.||...|||::.|..:|.||||||||:...:|||||||:||.
  Fly    53 PLAPKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYC 117

  Fly    95 VVLFVVGKPIYYMEMLLGQFSSRGIVQVFD-FAPLMRGVGYAQLLALGVLATYYASVMALTLRYF 158
            :.|...|.|::|||:.||||...|.:.::. ..|.::|||||..|....:..||.:::...:.|.
  Fly   118 LFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYL 182

  Fly   159 FDSFASELPWSFCREEWG-DGCVSASGGQPLQGQLSRNF----SSSTQLYLQRIVL-----NETD 213
            |.||.|:|||:.|...|. :.|:..:         |.||    :|..:.:.:|.||     |..|
  Fly   183 FASFTSKLPWTSCDNPWNTENCMQVT---------SENFTELATSPAKEFFERKVLESYKGNGLD 238

  Fly   214 SLEEGIGYPSGSLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYD 278
            .:    |....:|||.:...::.|...:.:||:|:||..:|.||.||||:.|||||.::||||.:
  Fly   239 FM----GPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADE 299

  Fly   279 GVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTS 343
            |:.|:|||:|.||...:||.:|.:|:||||...||.::..||||:|.:|.||||.|.::::..||
  Fly   300 GIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTS 364

  Fly   344 LLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVF-SLLFFAMLFMLG 407
            .|:|.:||.:||.:|:...| .|..|...||||.||.||:|||  .|...|| |::||.||..||
  Fly   365 FLAGFVIFSVLGYMAYVQKT-SIDKVGLEGPGLVFIVYPEAIA--TMSGSVFWSIIFFLMLITLG 426

  Fly   408 VGSNVGMVSCIMTVLKDQFVNV---KLWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFV 469
            :.|..|.:..::|.|.|::..|   :..:.|:.|....||..|..:|.||..::..::.:|....
  Fly   427 LDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLA 491

  Fly   470 SLVSAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYSLLTMRPLSY 534
            .|.....|...|.|.||..|...|.|.||..|...::||||:.::|:.:|.|.::|::..:.:..
  Fly   492 ILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEMLG 556

  Fly   535 NGQEFPLVYRVVGWCVSG----CIIGQLFYWAGYANFKQPKGSLKSRINNSIKPHSDWGPSDP 593
            ....:|.....|||.|:.    ||...:.|...:|:    ||..:.|:..|.:|..:.|...|
  Fly   557 EEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFAS----KGGCRQRLQESFQPEDNCGSVVP 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	186/488 (38%)
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	201/552 (36%)