Protein Alignment CG4476 and DAT

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 580
• Identity: 209/580 - (36%)
• Similarity: 314/580 - (54%)
• Gaps: 50/580 - (8%)

  Fly    51 RDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFS 115
            |:.|...::||:|.|..:|.|.||||||:...:|||||||:||.::|.|.|.|::|||:.|||.:
  Fly    27 RETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHN 91

  Fly   116 SRGIVQVFD-FAPLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASELPWSFCREEWG-DG 178
            .:|.:..:. ..||.:|:|||.:|....:..||..::|.:||:||.||.:.|||:.|...|. ..
  Fly    92 RKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPN 156

  Fly   179 C-------------------VSASGGQPL----------------QGQLSRNFSSSTQLYLQRIV 208
            |                   :.|.|.|.|                .|.: ..|.|:...|..|.:
  Fly   157 CRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHV-EGFQSAASEYFNRYI 220

  Fly   209 --LNETDSLEEGIGYPSGSLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRAL 271
              ||.::.:.: :|.....:||.|.|.:|.....:.:|:.:|||..:..|||||.|:.|||:|.|
  Fly   221 LELNRSEGIHD-LGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGL 284

  Fly   272 TLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVT 336
            ||||::.|:.|:|||.:..:.:.:||.:|.|||||||...|||::.|:|||::.:|||:||.:.:
  Fly   285 TLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTS 349

  Fly   337 TLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVFSLLFFA 401
            .:::.||.::|.:||.:||.:||..|.: |..|...||||.|:.||.|||.... ...::|:||.
  Fly   350 FINSATSFIAGFVIFSVLGYMAHTLGVR-IEDVATEGPGLVFVVYPAAIATMPA-STFWALIFFM 412

  Fly   402 MLFMLGVGSNVGMVSCIMTVLKDQFVNVK--LWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFH 464
            ||..||:.|:.|....|:|.|.|:|..:|  ..:.|..|..:.|:|||...|.||.:...|:|.:
  Fly   413 MLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRY 477

  Fly   465 GVTFVSLVSAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYSLLTM 529
            ...:..||:..||.|||.|||||.|..:|...|:......|:::||..|.|:.:|.|.||.|:..
  Fly   478 AAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGY 542

  Fly   530 RPLSYNGQEFPLVYRVVGWCVSGCIIGQLFYWAGYANFK--QPKGSLKSRINNSIKPHSD 587
            .||:|....:|.....:|||::|..:..:   ...|.||  ...|||:.|......|..|
  Fly   543 EPLTYADYVYPSWANALGWCIAGSSVVMI---PAVAIFKLLSTPGSLRQRFTILTTPWRD 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	190/514 (37%)
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	207/576 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440750
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850