Protein Alignment CG4476 and slc6a19b

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_956030.1
• Gene: slc6a19b / 326030
• ZFINID: ZDB-GENE-030131-4755
• Length: 651
• Species: Danio rerio
• Alignment Length: 649
• Identity: 188/649 - (28%)
• Similarity: 319/649 - (49%)
• Gaps: 103/649 - (15%)

  Fly    38 ALESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGK 102
            |||..|:. :...|..|.:..:::::|:...||||||||||:....:|||||:||:|::|...|.
Zfish    21 ALERLEVE-EAGDRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGI 84

  Fly   103 PIYYMEMLLGQFSSRGIVQVF-DFAPLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASEL 166
            |:.::|..:||...:|.|.|: ...|.|.|||.|.:....:::.||.:::|..:.|||:||...|
Zfish    85 PLLHLEFAIGQRLRKGSVGVWRTINPYMLGVGIASMCVSFLVSLYYNTIIAWVMWYFFNSFQDPL 149

  Fly   167 PWSFC--REEWGDGCVSASGGQPLQGQLSRNFSSSTQLYLQRIVLNETDSLEEGIGYPSGSL--- 226
            |||.|  .|       :.:|..|..|:     ||....:..|..||.:.::::     :|.|
Zfish   150 PWSQCPINE-------NRTGPIPECGK-----SSPVDYFWYRETLNTSAAIDD-----TGGLQVW 197

  Fly   227 -ALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWEK 290
             .|.|..:|..:.:..|||::::|||.||.:..||:|:.|.|:|.|||.|:.||:.:..||...:
Zfish   198 MVLCLISAWAVLYVCCIRGIETTGKAVYVTSTLPYLVLTIFLIRGLTLKGSVDGIKFLFTPDINE 262

  Fly   291 LLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGILG 355
            |..|..|.:|..|||:|.::.||.:|.:||||...:|..:||.|::.::.|||:.:..:|:.|:|
Zfish   263 LANPSTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEQDAVIISVINAFTSIYAATVIYSIIG 327

  Fly   356 NLAHE-------------------------------------SGTKDIASVVK------------ 371
            ..|.|                                     |.:.||.|.:.
Zfish   328 FRATERFDDCMNGNILTLLNTFDLPEGFINQSNYQDVFQSLNSTSPDIISSLSLKTCDLNNFLSE 392

  Fly   372 --AGPGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVNVKLW-- 432
              .|.|||||.:.:||.|..:.| ::|:|||.|||.||:.|..|.:..::..|:|..|..|.|
Zfish   393 GVEGTGLAFIVFTEAITKMPLSP-LWSVLFFIMLFCLGLSSMFGNIEGVLVPLQDLGVFPKSWPK 456

  Fly   433 -IIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKRLCQDAEY 496
             ||.....::..|||||::...|.:.:.|.|....:...|:.|..|:|.|.::||..|..:|..:
Zfish   457 EIISGVTCLVCCLVGLIFVQGSGNYWLALFDSFAGSIPLLIIAFSEMIGVVYVYGIDRFNEDLIF 521

  Fly   497 MLNIKTSNYYRICWSIVTPLVMLVILV--YSLLTMRPLSYN-----GQEFPLVYR--------VV 546
            |:..|.:.:::..|..::||:||.|.|  :|....:.:.|:     .:.||.:.:        |:
Zfish   522 MIGHKPNIFWQATWRFISPLIMLAIFVFYFSTTVTKEIFYSAWDPESENFPTLEKKPYPTWIYVI 586

  Fly   547 GWCVSG----CIIGQLFYWA--GYANFKQPKGSLK--SRINNSIKPHSDWGPSDPKKLMDYQMF 602
            .:.::|    .:.|...:.|  .|...|.|..|::  ..::..::.|.:...:...:..|.:::
Zfish   587 IFLLAGVPSLAVPGTAVFRAIRDYCCKKHPSASIQQLDSVSYKVQMHDEEVKTQKTEKFDQKLY 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	169/536 (32%)
slc6a19b	NP_956030.1	SLC6sbd_B0AT1	33..613	CDD:212085	179/597 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810