DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4476 and NAAT1

DIOPT Version :9

Sequence 1:	NP_648293.1	Gene:	CG4476 / 39056	FlyBaseID:	FBgn0035969	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_572219.1	Gene:	NAAT1 / 31457	FlyBaseID:	FBgn0029762	Length:	641	Species:	Drosophila melanogaster

Alignment Length:	618	Identity:	298/618 - (48%)
Similarity:	414/618 - (66%)	Gaps:	28/618 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VSGGLPKLETSRCAGSGEALLKPSLLPMALESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNV 74
            :.|..|...:|..:|:|      :....:.|.::.......|.|||:.||||||||::|||||||
  Fly     3 LKGVQPSNGSSNGSGNG------ATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNV 61

  Fly    75 WRFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFSSRGIVQVFDFAPLMRGVGYAQLLA 139
            |||||||.|||||||||||::|||::|||:||:||::|||:|:|.|:::...|...||||.|...
  Fly    62 WRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWSVVPGFVGVGYGQAFG 126

  Fly   140 LGVLATYYASVMALTLRYFFDSFASELPWSFCREEWGDGCVSAS---------GGQPLQGQLSRN 195
            ...:.:||:|::||||.|.|.||.||||||:||:|| ..||::.         .|..|..:.:||
  Fly   127 TICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEW-TNCVNSRPQEYVDNLLTGVSLANESARN 190

  Fly   196 FS------------SSTQLYLQRIVLNETDSLEEGIGYPSGSLALMLGISWLTVTLIIIRGVKSS 248
            .|            ||::||...:|:.|...:.:|:|.|...|.|.|.::|:.:.|:|:||||||
  Fly   191 LSGIVANDETEKLQSSSELYFLNVVIKEKLDISDGVGDPDWKLTLALFVAWVVIFLVIMRGVKSS 255

  Fly   249 GKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFG 313
            |||||.||||||||:|:||:||:||.||.||:::||.|||.:||.|.||..||.|.||||||..|
  Fly   256 GKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSG 320

  Fly   314 VIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAF 378
            .|||::|||||.|.:||||.|||||||.||||.|:.||.|||||||....::|..||::|.||||
  Fly   321 PIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAF 385

  Fly   379 ISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVNVKLWIIVVSLSVIGF 443
            |||||||:||:..||:||:|||.|||:||:||.|.:.|.|:|::.|||...|.|.:.::.||.||
  Fly   386 ISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWKVALTTSVCGF 450

  Fly   444 LVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRI 508
            |:||:|:|||||.|:||:||:|.|:|..:.|||||..:.|:||.:..|.|.|:|.|.:.|.|:|:
  Fly   451 LMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRV 515

  Fly   509 CWSIVTPLVMLVILVYSLLTMRPLSYNGQEFPLVYRVVGWCVSGCIIGQLFYWAGYANFKQPKGS 573
            |||..||::|::|.:||::|:.|:.|:...||....:.||.:......|...|..:...:.|:|:
  Fly   516 CWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGT 580

  Fly   574 LKSRINNSIKPHSDWGPSDPKKLMDYQMFLRNK 606
            ....:..|:||...|||::|:...::.:|...|
  Fly   581 YWKSLKASLKPSDRWGPANPEIRREWVIFKNQK 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	270/494 (55%)
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	270/493 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469616
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61415
OrthoDB	1	1.010	-	-		D14202at7147
OrthoFinder	1	1.000	-	-		FOG0008552
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.860